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Property and Equipment, net - Summary of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Sep. 30, 2017
Dec. 31, 2016
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 22,682 $ 21,969
Accumulated Depreciation (3,118) (942)
Property and equipment, net 19,564 21,027
Computer Equipment and Software [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 285 110
Furniture, Fixtures, and Other [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 2,104 2,044
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 6,392 2,970
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross 13,774 15,780
Construction Work in Progress [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment, gross $ 127 $ 1,065