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Share Capital - Schedule of Conditional Capital Reserved for Future Issuance (Detail) - shares
Sep. 30, 2017
Dec. 31, 2016
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 16,746,246 15,325,607
Employee Purchase Plans [Member]    
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 413,226 413,226
Bonds and Similar Debt Instruments [Member]    
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 4,919,700 4,919,700
Unvested Unissued Restricted Stock [Member]    
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 166,667 166,667
Outstanding Stock Options [Member]    
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 5,778,629 4,535,371
Stock Option Plan [Member]    
Class of Stock [Line Items]    
Conditional capital reserved for future issuance 5,468,024 5,290,643