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v3.20.2

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2020 | Sep. 30, 2019
Operating activities: |  |
Net loss | $ (241,826) | $ 36,316
Reconciliation of net loss to net cash used in operating activities: |  |
Depreciation and amortization | 6,618 | 3,293
Equity-based compensation | 47,088 | 32,200
Loss from equity method investment |  | 5,467
Other expense, non-cash | 979 |
Changes in: |  |
Accounts receivable | (11) | 49
Prepaid expenses and other assets | 19,273 | (25,342)
Accounts payable and accrued expenses | 17,394 | 420
Deferred revenue | (350) | 1,714
Operating lease assets and liabilities | (282) | (689)
Other liabilities, net | (6,037) | (127)
Net cash (used in) provided by operating activities | (157,154) | 53,301
Investing activities: |  |
Purchase of property, plant and equipment | (12,119) | (5,732)
Purchases of marketable securities | (325,316) |
Maturities of marketable securities | 509 |
Net cash used in investing activities | (336,926) | (5,732)
Financing activities: |  |
Proceeds from issuance of common shares, net of issuance costs | 582,225 | 121,216
Proceeds from exercise of options and ESPP contributions, net of issuance costs | 21,300 | 5,049
Net cash provided by financing activities | 603,525 | 126,265
Effect of exchange rate changes on cash | 5 | (14)
Increase in cash | 109,450 | 173,820
Cash, cash equivalents and restricted cash, beginning of period | 948,812 | 459,812
Cash, cash equivalents and restricted cash, end of period | 1,058,262 | 633,632
Supplemental disclosure of non-cash investing and financing activities |  |
Property and equipment purchases in accounts payable and accrued expenses | 2,863 | 428
Equity issuance costs in accounts payable and accrued expenses | $ 5,955 | $ 739

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