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Leases (Tables)

12 Months Ended

Dec. 31, 2020

The following table summarizes the lease assets and liabilities as of December 31, 2020 and 2019 (in thousands):

	As of December 31,
	2020		2019
Assets
Operating lease assets	$	50,865	$	41,502
Total lease assets		50,865		41,502
Liabilities
Current
Operating lease liabilities		11,362		8,489
Non-current
Operating lease liabilities, net of current portion		50,067		44,050
Total lease liabilities	$	61,429	$	52,539

Summary of Operating Lease Costs Included in Research and Development and General and Administrative Expense, as well as Sublease Income

The following table summarizes operating lease costs included in research and development and general and administrative expense, as well as sublease income for the twelve months ended December 31, 2020 and 2019 (in thousands):

	Years Ended December 31,
	2020			2019
Operating lease costs	$	14,342		$	8,067
Short-term lease costs		7,339			4,554
Variable lease costs		6,368			4,282
Sublease income		(587	)		(525	)
Net lease cost	$	27,462		$	16,378

Summary of Maturity of Undiscounted Payments Due under Lease Liabilities and Present Value of Those Liabilities

The following table summarizes the maturity of undiscounted payments due under lease liabilities and the present value of those liabilities as of December 31, 2020 (in thousands):

	Total
2021	$	17,020
2022		13,815
2023		12,650
2024		10,761
2025		10,265
Thereafter		37,206
Total	$	101,717
Present value adjustment		(40,288	)
Present value of lease liabilities	$	61,429

Summary of Lease Term and Discount Rate

The following table summarizes the lease term and discount rate as of December 31, 2020 and 2019:

	As of December 31,
	2020			2019
Weighted-average remaining lease term (years)
Operating leases		9.1			6.0
Weighted-average discount rate
Operating leases		9.3	%		9.9	%

Lessee, Operating Lease Cash Flow Payments

The following table summarizes the cash paid for amounts included in the measurement of lease liabilities for the year ended December 31, 2020 and 2019 (in thousands):

	Years Ended December 31,
	2020			2019
Cash paid for amounts included in measurement of lease liabilities:
Operating cash flows used in operating leases	$	(13,161	)	$	(8,420	)
Operating lease non-cash items:
Right-of-use assets increased through lease modifications and reassessments		3,169			826
Right-of-use assets obtained in exchange for operating lease liabilities		13,956			18,088