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Share Capital - Additional Information (Detail)		1 Months Ended								12 Months Ended
	Feb. 16, 2021 USD ($) $ / shares shares	Jan. 31, 2021 USD ($) $ / shares shares	Jul. 31, 2020 USD ($) $ / shares shares	Nov. 30, 2019 USD ($) $ / shares shares	Aug. 31, 2019 USD ($)	Sep. 30, 2018 USD ($) $ / shares shares	Aug. 31, 2018 USD ($)	Jan. 31, 2018 USD ($) $ / shares shares	Oct. 31, 2016 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares	Dec. 31, 2019 USD ($) $ / shares shares	Dec. 31, 2018 USD ($)	Dec. 31, 2020 SFr / shares	Dec. 31, 2019 SFr / shares	Aug. 31, 2019 SFr / shares
Class of Stock [Line Items]
Common stock, shares authorized | shares										115,172,786	103,901,006
Common shares, par value | SFr / shares													SFr 0.03	SFr 0.03
Capital reserved for future issuance | shares										2,906,383
Proceeds from issuance of common shares										$ 982,289,000	$ 415,019,000	$ 307,053,000
Common Stock, Voting Rights										one vote for each Common Share
Dividends declared and paid										$ 0
IPO [Member]
Class of Stock [Line Items]
Common shares sold | shares									4,400,000
Common shares price per share | $ / shares									$ 14.00
Proceeds from issuance of common shares									$ 53,700,000
Equity issuance costs									$ 8,300,000
Private Placement [Member] | Bayer Global Investments B.V [Member]
Class of Stock [Line Items]
Common shares sold | shares									2,500,000
Common shares price per share | $ / shares									$ 14.00
Proceeds from issuance of common shares									$ 35,000,000.0
Underwritten Public Offering [Member]
Class of Stock [Line Items]
Common shares sold | shares			7,400,000	4,900,000		4,200,000		5,700,000
Common shares price per share | $ / shares			$ 70.00	$ 64.50		$ 47.50		$ 22.75
Proceeds from issuance of common shares			$ 489,700,000	$ 297,400,000		$ 184,500,000		$ 122,600,000
Equity issuance costs			$ 27,600,000	$ 17,800,000		$ 12,400,000		$ 8,200,000
Payments of stamp taxes related to securities											$ 3,000,000.0	$ 3,100,000
Additional equity issuance costs of stamp taxes										4,900,000
Payable of stamp taxes related to securities										4,900,000
2018 ATM [Member] | Sales Agreement With Jefferies LLC [Member]
Class of Stock [Line Items]
Common shares sold | shares											2,800,000
Proceeds from issuance of common shares											$ 120,600,000
Equity issuance costs											4,400,000
Payments of stamp taxes related to securities										$ 300,000	$ 900,000
Average issue price of common shares | $ / shares											$ 44.38
Accrued stamp taxes											$ 300,000
2018 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Maximum [Member]
Class of Stock [Line Items]
Aggregate estimated gross proceeds							$ 125,000,000.0
2019 ATM [Member] | Sales Agreement With Jefferies LLC [Member]
Class of Stock [Line Items]
Common shares, par value | SFr / shares															SFr 0.03
Common shares sold | shares										2,200,000
Proceeds from issuance of common shares										$ 195,500,000
Equity issuance costs										$ 4,500,000
Average issue price of common shares | $ / shares										$ 89.47
2019 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Maximum [Member]
Class of Stock [Line Items]
Aggregate estimated gross proceeds					$ 200,000,000.0
2020 ATM [Member] | Sales Agreement With Jefferies LLC [Member]
Class of Stock [Line Items]
Common shares sold | shares										1,800,000
Proceeds from issuance of common shares										$ 298,000,000.0
Equity issuance costs										4,500,000
Payments of stamp taxes related to securities										4,900,000
Payable of stamp taxes related to securities										$ 4,000,000.0
Average issue price of common shares | $ / shares										$ 169.57
2020 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Subsequent Event [Member]
Class of Stock [Line Items]
Common shares sold | shares		300,000
Equity issuance costs		$ 700,000
Payments of stamp taxes related to securities		500,000
Aggregate estimated gross proceeds		$ 46,700,000
Average issue price of common shares | $ / shares		$ 162.46
2020 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Maximum [Member]
Class of Stock [Line Items]
Aggregate estimated gross proceeds					$ 350,000,000.0
2021 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Subsequent Event [Member]
Class of Stock [Line Items]
Common shares sold | shares	1,100,000
Equity issuance costs	$ 2,400,000
Payments of stamp taxes related to securities	1,800,000
Aggregate estimated gross proceeds	$ 177,800,000
Average issue price of common shares | $ / shares	$ 169.82
2021 ATM [Member] | Sales Agreement With Jefferies LLC [Member] | Maximum [Member] | Subsequent Event [Member]
Class of Stock [Line Items]
Aggregate estimated gross proceeds		$ 600,000,000.0

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