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Subsequent Events - Additional Information (Detail) - A&R JDCA [Member] - USD ($) $ in Millions | Jul. 01, 2021 | Apr. 16, 2021
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Forecast [Member] |  |
Subsequent Event [Line Items] |  |
Percentage of net profits and net losses | 40.00% |
Forecast [Member] | Vertex Pharmaceuticals Inc [Member] |  |
Subsequent Event [Line Items] |  |
Percentage of net profits and net losses | 60.00% |
Subsequent Event [Member] | Vertex Pharmaceuticals Inc [Member] |  |
Subsequent Event [Line Items] |  |
Up-front payment receivable |  | $ 900
Milestone payment receivable upon receipt of first marketing approval |  | $ 200

X
- Definition Milestone payment receivable. + References No definition available. + Details
Name: | crsp_MilestonePaymentReceivable
Namespace Prefix: | crsp_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Percentage of net profit and net losses. + References No definition available. + Details
Name: | crsp_PercentageOfNetProfitAndNetLosses
Namespace Prefix: | crsp_
Data Type: | num:percentItemType
Balance Type: | na
Period Type: | instant

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- Definition Up-front payment receivable. + References No definition available. + Details
Name: | crsp_UpFrontPaymentReceivable
Namespace Prefix: | crsp_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References No definition available. + Details
Name: | us-gaap_SubsequentEventLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | srt_StatementScenarioAxis=srt_ScenarioForecastMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_TypeOfArrangementAxis=crsp_AmendedAndRestatedJointDevelopmentAndCommercializationAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_CounterpartyNameAxis=crsp_VertexPharmaceuticalsIncMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |