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Equity-based Compensation - Fair Value of Each Option Issued to Employees and Non-employees Estimated Using Black-Scholes Option-Pricing Model (Detail) - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-based Payment Arrangement [Abstract]      
Options granted 1,616,255 2,182,773 2,832,784
Weighted-average exercise price $ 124.32 $ 68.91 $ 39.16
Weighted-average grant date fair value $ 77.38 $ 42.28 $ 24.57
Expected volatility 70.30% 69.20% 68.90%
Expected term (in years) 6 years 6 years 6 years
Risk-free interest rate 1.00% 0.60% 2.20%
Expected dividend yield 0.00% 0.00% 0.00%