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v3.25.0.1

Segment Information - Schedule of Reportable Segment Profit and Loss, Including Significant Expense Categories, Attributable to the Company's Reportable Segment (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Revenues [Abstract] |  |  |
Total revenue | $ 37,314 | $ 371,206 | $ 1,198
Operating Expenses [Abstract] |  |  |
Research and development expense | 320,653 | 387,332 | 461,645
General and administrative expense | 72,977 | 76,162 | 102,464
Collaboration expense, net | 110,250 | 130,250 | 110,250
Stock-based compensation expense | 86,567 | 81,028 | 97,947
Depreciation expense | 19,200 | 19,800 | 24,100
Other income, net | 103,901 | 71,816 | 22,661
Provision (benefit) for income taxes | 3,587 | 2,888 | (325)
Segment net income | (366,252) | (153,610) | (650,175)
Net loss | (366,252) | (153,610) | (650,175)
Operating Segments [Member] |  |  |
Operating Expenses [Abstract] |  |  |
Research and development expense | 262,427 | 330,121 | 397,067
General and administrative expense | 25,453 | 32,589 | 45,012
Collaboration expense, net | 110,250 | 130,250 | 110,250
Stock-based compensation expense | 86,567 | 81,028 | 97,947
Depreciation expense | 19,183 | 19,756 | 24,083
Other income, net | (103,901) | (71,816) | (22,661)
Provision (benefit) for income taxes | 3,587 | 2,888 | (325)
Segment net income | (366,252) | (153,610) | (650,175)
Adjustments or reconciling items | 0 | 0 | 0
Net loss | (366,252) | (153,610) | (650,175)
Collaboration Revenue [Member] |  |  |
Revenues [Abstract] |  |  |
Total revenue | 35,000 | 370,000 | 436
Collaboration Revenue [Member] | Operating Segments [Member] |  |  |
Revenues [Abstract] |  |  |
Total revenue | 35,000 | 370,000 | 436
Grant Revenue [Member] |  |  |
Revenues [Abstract] |  |  |
Total revenue | 2,314 | 1,206 | 762
Grant Revenue [Member] | Operating Segments [Member] |  |  |
Revenues [Abstract] |  |  |
Total revenue | $ 2,314 | $ 1,206 | $ 762

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