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Commitments and Contingencies - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Contingencies And Commitments [Line Items] |  |  |
Defer option specified cost | $ 110,300 | $ 110,300 | $ 110,300
Deferred Finance Costs, Share Lending Arrangement, Issuance Costs | 102,800 | 80,900 | $ 36,100
Defer option amount | 0 |  |
Vertex Pharmaceuticals Incorporated and Certain of its Subsidiaries [Member] |  |  |
Contingencies And Commitments [Line Items] |  |  |
Milestone payment receivable | 200,000 |  |
Cost excluded from license agreement |  | $ 110,300 |
2015 Collaboration Agreement [Member] | Vertex Pharmaceuticals Incorporated and Certain of its Subsidiaries [Member] |  |  |
Contingencies And Commitments [Line Items] |  |  |
Milestone payment receivable | $ 395,000 |  |

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- Definition Accounting analysis, defer option amount. + References No definition available. + Details
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Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Accounting Analysis, defer option specified cost. + References No definition available. + Details
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Balance Type: | debit
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- Definition Contingencies and commitments. + References No definition available. + Details
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- Definition Cost Excluded from License Agreement + References No definition available. + Details
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Balance Type: | debit
Period Type: | duration

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- Definition Deferred finance costs, share lending arrangement, issuance costs. + References No definition available. + Details
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Namespace Prefix: | crsp_
Data Type: | xbrli:monetaryItemType
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- Definition Milestone payment receivable. + References No definition available. + Details
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Namespace Prefix: | crsp_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Details
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Namespace Prefix: |
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Balance Type: |
Period Type: |

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- Details
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Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |