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Leases - Summary of Operating Lease Costs Included in Research and Development and General and Administrative Expense, as well as Sublease Income (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Leases [Abstract]
Operating lease costs	$ 24,417	$ 25,870	$ 34,896
Short-term lease costs	40	0	824
Variable lease costs	12,364	14,387	11,882
Sublease income	(573)	(137)	0
Net lease cost	$ 36,248	$ 40,120	$ 47,602

X

- Definition

Amount of lease cost recognized by lessee for lease contract.

+ References

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-Topic 842
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-Name Accounting Standards Codification
-Section 55
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No definition available.

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- Definition

Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

+ References

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- Definition

Amount of short-term lease cost, excluding expense for lease with term of one month or less.

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- Definition

Amount of sublease income excluding finance and operating lease expense.

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X

- Definition

Amount of variable lease cost, excluded from lease liability, recognized when obligation for payment is incurred for finance and operating leases.

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