<SEC-DOCUMENT>0001309108-22-000129.txt : 20220606
<SEC-HEADER>0001309108-22-000129.hdr.sgml : 20220606
<ACCEPTANCE-DATETIME>20220606205905
ACCESSION NUMBER:		0001309108-22-000129
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20220602
FILED AS OF DATE:		20220606
DATE AS OF CHANGE:		20220606

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Tinto Melanie J
		CENTRAL INDEX KEY:			0001732729

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32426
		FILM NUMBER:		22999647

	MAIL ADDRESS:	
		STREET 1:		C/O WEX INC.
		STREET 2:		97 DARLING AVENUE
		CITY:			SOUTH PORTLAND
		STATE:			ME
		ZIP:			04106

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			WEX Inc.
		CENTRAL INDEX KEY:			0001309108
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-BUSINESS SERVICES, NEC [7389]
		IRS NUMBER:				010526993
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		97 DARLING AVENUE
		CITY:			SOUTH PORTLAND
		STATE:			ME
		ZIP:			04106
		BUSINESS PHONE:		(207) 773-8171

	MAIL ADDRESS:	
		STREET 1:		97 DARLING AVENUE
		CITY:			SOUTH PORTLAND
		STATE:			ME
		ZIP:			04106

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Wright Express CORP
		DATE OF NAME CHANGE:	20041118
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wf-form4_165456352887769.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2022-06-02</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001309108</issuerCik>
        <issuerName>WEX Inc.</issuerName>
        <issuerTradingSymbol>WEX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001732729</rptOwnerCik>
            <rptOwnerName>Tinto Melanie J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O WEX INC.</rptOwnerStreet1>
            <rptOwnerStreet2>97 DARLING AVENUE</rptOwnerStreet2>
            <rptOwnerCity>SOUTH PORTLAND</rptOwnerCity>
            <rptOwnerState>ME</rptOwnerState>
            <rptOwnerZipCode>04106</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Human Resources Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2022-06-02</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>782</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>172.22</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>6751</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>389</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>401(k)</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">The price listed is a weighted average price for all shares sold. All shares were sold for between $172.21 and $172.24. Upon request, the reporting person will provide the Securities and Exchange Commission, WEX Inc. or any security holder of WEX Inc. with full information regarding the number of shares sold at each separate purchase price.</footnote>
        <footnote id="F2">Between March 21, 2022 and June 3, 2022 the reporting person acquired 15 shares of WEX Inc. common stock under the WEX Inc. 401(k) savings plan. The information in this report is based on a plan statement dated June 3, 2022.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Hilary Rapkin, as attorney-in-fact for Melanie J. Tinto</signatureName>
        <signatureDate>2022-06-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
