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Acquisitions - fair values determination of assets acquired and liabilities assumed in acquisition (Details) - USD ($) $ in Thousands | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
--- | --- | --- | ---
Business Acquisition [Line Items] |  |  |
Goodwill | $ 1,295,852 | $ 1,323,553 | $ 1,354,203
Business Combinations 2015 |  |  |
Business Acquisition [Line Items] |  |  |
Current assets | 10,515 |  |
Property, plant and equipment | 2,877 |  |
Goodwill | 19,725 |  |
Other noncurrent assets | 45 |  |
Total assets acquired | 102,106 |  |
Current liabilities | 3,018 |  |
Deferred tax liabilities | 2,477 |  |
Other noncurrent liabilities | 138 |  |
Liabilities assumed | 5,633 |  |
Net assets acquired | 96,473 |  |
Business Combinations 2015 | Intellectual property |  |  |
Business Acquisition [Line Items] |  |  |
Intangible Assets | 33,017 |  |
Business Combinations 2015 | In-process research and development |  |  |
Business Acquisition [Line Items] |  |  |
Intangible Assets | 17,908 |  |
Business Combinations 2015 | Customer relationships |  |  |
Business Acquisition [Line Items] |  |  |
Intangible Assets | 8,387 |  |
Business Combinations 2015 | Distribution rights |  |  |
Business Acquisition [Line Items] |  |  |
Intangible Assets | 7,738 |  |
Business Combinations 2015 | Noncompete agreements |  |  |
Business Acquisition [Line Items] |  |  |
Intangible Assets | $ 1,894 |  |

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