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Restructuring and impairment charges - Expected costs to be incurred (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | ---
Restructuring Cost and Reserve [Line Items] |  |
Deferred tax assets, valuation allowance | $ 91,531 | $ 143,177
2022 restructuring plan |  |
Restructuring Cost and Reserve [Line Items] |  |
Deferred tax assets, valuation allowance | 8,100 |
2022 restructuring plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 39,000 |
2022 restructuring plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 48,000 |
Respiratory divestiture plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | 24,000
Respiratory divestiture plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | 30,000
One-time Termination Benefits | 2022 restructuring plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 18,000 |
One-time Termination Benefits | 2022 restructuring plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 22,000 |
Other costs | 2022 restructuring plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 1,000 |
Other costs | 2022 restructuring plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 1,000 |
Restructuring charges | 2022 restructuring plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 19,000 |
Restructuring charges | 2022 restructuring plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 23,000 |
Restructuring charges | Respiratory divestiture plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | 5,000
Restructuring charges | Respiratory divestiture plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | 8,000
Restructuring related charges | 2022 restructuring plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | 20,000 |
Restructuring related charges | 2022 restructuring plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges | $ 25,000 |
Restructuring related charges | Respiratory divestiture plan | Minimum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | 19,000
Restructuring related charges | Respiratory divestiture plan | Maximum |  |
Restructuring Cost and Reserve [Line Items] |  |
Expected restructuring charges |  | $ 22,000

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