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Debt - Additional Information (Details) | 1 Months Ended | 9 Months Ended | 12 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Jun. 30, 2017 USD ($) | Dec. 31, 2015 USD ($) Tranche | Jun. 30, 2014 USD ($) $ / shares shares | Nov. 30, 2012 USD ($) shares | Sep. 30, 2017 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2016 USD ($) | Dec. 01, 2016 USD ($) | Aug. 31, 2016 USD ($) | Dec. 04, 2015 USD ($) | Jun. 30, 2015 $ / shares shares
Series D Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants issued to purchase shares | shares |  |  | 20,136 |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares |  |  | $ 7.31 |  |  |  |  |  |  |  |
CHCF Note |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Debt instrument maturity date |  |  |  | Nov. 30, 2016 |  |  |  |  |  |  |
Debt balance |  |  |  |  | $ 1,600,000 |  | $ 1,500,000 |  |  |  |
Proceeds from long-term debt, net of issuance costs |  |  |  | $ 1,500,000 |  |  |  |  |  |  |
Debt instrument accrues simple interest rate |  |  |  | 2.00% |  |  |  |  |  |  |
Debt instrument extended maturity date |  |  |  |  | May 31, 2018 |  |  |  |  |  |
CHCF Note | Series D Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants issued to purchase shares | shares |  |  |  | 22,807 |  |  |  |  |  |  | 8,552
Exercise price of warrants | $ / shares |  |  |  |  |  |  |  |  |  |  | $ 6.58
Pharmakon Loan Agreement |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity |  | $ 55,000,000 |  |  |  |  |  |  |  |  |
Number of tranches for loans | Tranche |  | 2 |  |  |  |  |  |  |  |  |
Paid in kind, interest percentage |  |  |  |  | 50.00% |  |  |  |  |  |
Debt instrument, covenant description |  |  |  |  | The Company is subject to a financial covenant related to minimum trailing revenue targets that begins in June 2017, and is tested on a semi-annual basis. The minimum net revenue covenant ranges from $44.7 million for the period ended June 30, 2017 to $102.6 million for the period ended December 31, 2021. To date all minimum revenue targets have been achieved. The minimum net revenues financial covenant has a 45-day equity cure period following required delivery date of the financial statements. |  |  |  |  |  |
Debt instrument, covenant compliance minimum net revenue target next twelve months | $ 44,700,000 |  |  |  |  |  |  |  |  |  |
Debt instrument, covenant equity cure period |  |  |  |  | 45 days |  |  |  |  |  |
Debt instrument maturity date |  |  |  |  | Dec. 31, 2021 |  |  |  |  |  |
Debt balance |  |  |  |  | $ 32,100,000 |  | 30,800,000 |  |  |  |
Pharmakon Loan Agreement | Silicon Valley Bank |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Repayment of bank debt |  | $ 4,900,000 |  |  |  |  |  |  |  |  |
Pharmakon Loan Agreement | Scenario Forecast |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Debt instrument, covenant compliance minimum net revenue fifth year |  |  |  |  |  | $ 102,600,000 |  |  |  |  |
Pharmakon Loan Agreement | Tranche A Loans |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity |  |  |  |  |  |  |  |  |  | $ 30,000,000 |
Debt instrument, fixed interest rate |  |  |  |  | 9.50% |  |  |  |  |  |
Debt instrument, periodic payment |  |  |  |  | quarterly |  |  |  |  |  |
Debt instrument, interest due and payable |  |  |  |  | 50.00% |  |  |  |  |  |
Pharmakon Loan Agreement | Tranche B Loans |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity |  |  |  |  |  |  |  | $ 25,000,000 |  |  |
Loan and Security Agreement |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from long-term debt, net of issuance costs |  |  | $ 4,900,000 |  |  |  |  |  |  |  |
Debt borrowed additional advance |  |  | $ 5,000,000 |  |  |  |  |  |  |  |
Repayment of debt |  | 4,900,000 |  |  |  |  |  |  |  |  |
Loan and Security Agreement | Series D Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants issued to purchase shares | shares |  |  | 20,136 |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares |  |  | $ 7.31 |  |  |  |  |  |  |  |
Warrants expiry period |  |  |  |  | 2024-06 |  |  |  |  |  |
SVB Loan Agreement |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity |  | $ 15,000,000 |  |  |  |  |  |  |  |  |
Credit facility expiration date |  |  |  |  | Dec. 04, 2018 |  |  |  |  |  |
Debt instrument variable rate basis trailing period of revenue |  | 6 months |  |  |  |  |  |  |  |  |
Borrowing capacity description |  |  |  |  | Any principal amount outstanding under the SVB revolving credit line shall bear interest at a floating rate per annum equal to the rate published by The Wall Street Journal as the “Prime Rate” plus 0.25%, are tied to the Company’s trailing six-month revenue and subject to certain revenue targets. The Company may borrow up to 80% of its eligible accounts receivable, up to the maximum of $15.0 million. |  |  |  |  |  |
SVB Loan Agreement | San Francisco Office | Standby Letters of Credit |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Letter of credit |  |  |  |  |  |  |  |  | $ 3,100,000 |  |
SVB Loan Agreement | Maximum |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of eligible accounts receivable for borrowings |  | 80.00% |  |  |  |  |  |  |  |  |
Credit facility borrowing capacity |  |  |  |  | $ 7,700,000 |  | $ 2,500,000 |  |  |  |
SVB Loan Agreement | Prime Rate |  |  |  |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |  |  |  |
Debt instrument interest rate spread |  | 0.25% |  |  |  |  |  |  |  |  |

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- Definition Description of minimum financial levels (for example, tangible net worth and working capital) and achievement of certain financial ratios (for example, working capital ratio and debt service coverage ratio), and adherence to certain clauses which generally require or restrict certain actions (for example, entering into a debt arrangement with equal or greater seniority, and selling or discontinuing a certain business segment or material subsidiary) to be in compliance with the covenant clauses of the debt agreement. May also include a discussion of the adverse consequences that would result if the entity violates or fails to satisfy the covenants. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 470 -Section 50 -Paragraph 3 -Subparagraph (g) -URI http://asc.fasb.org/extlink&oid=75038535&loc=d3e64711-112823 + Details
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- Definition The carrying value as of the balance sheet date of the current and noncurrent portions of long-term obligations drawn from a line of credit, which is a bank's commitment to make loans up to a specific amount. Examples of items that might be included in the application of this element may consist of letters of credit, standby letters of credit, and revolving credit arrangements, under which borrowings can be made up to a maximum amount as of any point in time conditional on satisfaction of specified terms before, as of and after the date of drawdowns on the line. Includes short-term obligations that would normally be classified as current liabilities but for which (a) postbalance sheet date issuance of a long term obligation to refinance the short term obligation on a long term basis, or (b) the enterprise has entered into a financing agreement that clearly permits the enterprise to refinance the short-term obligation on a long term basis and the following conditions are met (1) the agreement does not expire within 1 year and is not cancelable by the lender except for violation of an objectively determinable provision, (2) no violation exists at the BS date, and (3) the lender has entered into the financing agreement is expected to be financially capable of honoring the agreement. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(16)) -URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(16)) -URI http://asc.fasb.org/extlink&oid=6876686&loc=d3e534808-122878 + Details
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