<SEC-DOCUMENT>0001967722-23-000005-index.html : 20230309
<SEC-HEADER>0001967722-23-000005.hdr.sgml : 20230309
<ACCEPTANCE-DATETIME>20230309182634
ACCESSION NUMBER:		0001967722-23-000005
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20230306
FILED AS OF DATE:		20230309
DATE AS OF CHANGE:		20230309

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mazzacco Catherine
		CENTRAL INDEX KEY:			0001967722

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38210
		FILM NUMBER:		23721098

	MAIL ADDRESS:	
		STREET 1:		C/O KRYSTAL BIOTECH, INC.
		STREET 2:		2100 WHARTON STREET, SUITE 701
		CITY:			PITTSBURGH
		STATE:			PA
		ZIP:			15203

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Krystal Biotech, Inc.
		CENTRAL INDEX KEY:			0001711279
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				821080209
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2100 WHARTON STREET
		STREET 2:		SUITE 701
		CITY:			PITTSBURGH
		STATE:			PA
		ZIP:			15203
		BUSINESS PHONE:		(412) 586-5830

	MAIL ADDRESS:	
		STREET 1:		2100 WHARTON STREET
		STREET 2:		SUITE 701
		CITY:			PITTSBURGH
		STATE:			PA
		ZIP:			15203
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>wf-form3_167840438290862.xml
<DESCRIPTION>FORM 3
<TEXT>
Document 1 - file: wf-form3_167840438290862.html

Document 1 - RAW XML: wf-form3_167840438290862.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>krystal-section16poamazz.htm
<DESCRIPTION>POWER OF ATTORNEY
<TEXT>
Document 2 - file: krystal-section16poamazz.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>krystal-section16poamazz001.jpg
<DESCRIPTION>POWER OF ATTORNEY
<TEXT>
Document 3 - file: krystal-section16poamazz001.jpg

</DOCUMENT>
</SEC-DOCUMENT>