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Selected quarterly financial data | 12 Months Ended
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Dec. 31, 2014
Selected quarterly financial data |
Selected quarterly financial data | 17. Selected quarterly financial data (Unaudited) The following financial information reflects all normal recurring adjustments, which are, in the opinion of management, necessary for a fair statement of the results of the interim periods. Summarized quarterly data for 2014 and 2013 are as follows:
|  | For the quarters ending |
|  | March 31 |  | June 30 |  | September 30 |  | December 31 |
2014: |  |  |  |  |  |  |  |  |  |  |  |  |
Net product sales |  | $ | — |  | $ | — |  | $ | 81 |  | $ | 636 |
Collaboration and grant revenue |  |  | 9,217 |  |  | 1,677 |  |  | 1,613 |  |  | 12,022 |
Operating expenses |  |  | 23,429 |  |  | 27,046 |  |  | 29,295 |  |  | 44,888 |
Loss from operations |  |  | (14,212 | ) |  | (25,369 | ) |  | (27,601 | ) |  | (32,230 | )
Net loss attributable to common stockholders |  |  | (14,098 | ) |  | (25,104 | ) |  | (27,282 | ) |  | (27,269 | )
Basic net loss per common share(1) |  | $ | (0.58 | ) | $ | (0.86 | ) | $ | (0.93 | ) | $ | (0.84 | )
Diluted net loss per common share(1) |  | $ | (0.58 | ) | $ | (0.86 | ) | $ | (0.93 | ) | $ | (0.84 | )
2013: |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and grant revenue |  | $ | 7,142 |  | $ | 6,854 |  | $ | 16,290 |  | $ | 4,411 |
Operating expenses |  |  | 15,718 |  |  | 21,307 |  |  | 20,565 |  |  | 22,503 |
Loss from operations |  |  | (8,576 | ) |  | (14,453 | ) |  | (4,276 | ) |  | (18,093 | )
Net loss |  |  | (14,685 | ) |  | (14,587 | ) |  | (4,416 | ) |  | (17,886 | )
Deemed dividend |  |  | (18,249 | ) |  | — |  |  | — |  |  | — |
Gain on exchange of convertible preferred stock in connection with recapitalization |  |  | 3,391 |  |  | — |  |  | — |  |  | — |
Net income (loss) attributable to common stockholders |  |  | (29,543 | ) |  | (14,587 | ) |  | (4,416 | ) |  | (17,886 | )
Basic net income (loss) per common share(1) |  | $ | (6,527.30 | ) | $ | (5.51 | ) | $ | (0.19 | ) | $ | (0.75 | )
Diluted net income (loss) per common share(1) |  | $ | (6,527.30 | ) | $ | (5.51 | ) | $ | (0.19 | ) | $ | (0.75 | )
(1) | The amounts were computed independently for each quarter and the sum of the quarters may not total the annual amounts.

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- Definition The entire disclosure for the quarterly financial data in the annual financial statements. The disclosure may include a tabular presentation of financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income or loss before extraordinary items and earnings per share data. It also includes an indication if the information in the note is unaudited, comments on the aggregate effect of year-end adjustments, and an explanation of matters or transactions that affect comparability or are pertinent to an understanding of the information furnished. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=6372559&loc=d3e765-108305 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6372559&loc=d3e725-108305 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=35737889&loc=d3e1280-108306 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 6 -Section G -Subsection 1 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K (SK) -Number 229 -Section 302 -Paragraph a + Details
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