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Consolidated Statements of Convertible Preferred Stock and Changes in Stockholders' Equity (Deficit) (USD $) | Series A-G convertible preferred stock | Series One-Three convertible preferred stock | Series Four convertible preferred stock | Series Five convertible preferred stock | Common stock | Additional paid-in capital | Accumulated other comprehensive income (loss) | Accumulated deficit | Total
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Balance at Dec. 31, 2011 |  |  |  |  | $ 133 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | $ 12,007,007 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  | $ (250,611,829)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | $ (238,604,689)us-gaap_StockholdersEquity
Balance, beginning of period at Dec. 31, 2011 | 214,379,914 us-gaap_TemporaryEquityCarryingAmountAttributableToParent / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember |  |  |  |  |  |  |  |
Balance (in shares) at Dec. 31, 2011 |  |  |  |  | 132,122 us-gaap_SharesIssued / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Balance, beginning of period (in shares) at Dec. 31, 2011 | 154,728,267 us-gaap_TemporaryEquitySharesIssued / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember |  |  |  |  |  |  |  |
Increase (decrease) in temporary equity |  |  |  |  |  |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock | (211,423,085)ptct_TemporaryEquityConvertedIssuedDuringPeriodValueExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember | 80,823,768 ptct_TemporaryEquityConvertedIssuedDuringPeriodValueExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember |  |  |  |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock (in shares) | (149,560,902)ptct_TemporaryEquityConvertedIssuedDuringPeriodSharesExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember | 15,038,259 ptct_TemporaryEquityConvertedIssuedDuringPeriodSharesExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember |  |  |  |  |  |  |
Conversion of series of convertible preferred stock to common stock | (2,956,829)us-gaap_TemporaryEquityEliminationAsPartofReorganization / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember |  |  |  |  |  |  |  |
Conversion of series of convertible preferred stock to common stock (in shares) | (5,167,365)us-gaap_ConversionOfStockSharesConverted1 / us-gaap_StatementClassOfStockAxis = ptct_SeriesAToGConvertiblePreferredStockMember |  |  |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock |  |  |  |  |  | 159,954,069 ptct_AdjustmentsToAdditionalPaidInCapitalDecreaseInCarryingAmountOfRedeemablePreferredStock / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 159,954,069 ptct_AdjustmentsToAdditionalPaidInCapitalDecreaseInCarryingAmountOfRedeemablePreferredStock
Conversion of series of convertible preferred stock to common stock |  |  |  |  | 412 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 2,956,417 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 2,956,829 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
Conversion of series of convertible preferred stock to common stock (in shares) |  |  |  |  | 413,223 us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Beneficial conversion charge |  |  |  |  |  | 377,787 ptct_AdjustmentsToAdditionalPaidInCapitalBeneficialConversionCharge / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  | (377,787)ptct_AdjustmentsToAdditionalPaidInCapitalBeneficialConversionCharge / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Share-based compensation expense |  |  |  |  |  | 2,288,392 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 2,288,392 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
Net loss |  |  |  |  |  |  |  | (26,235,102)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | (26,235,000)us-gaap_NetIncomeLoss
Balance at Dec. 31, 2012 |  |  |  |  | 545 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 177,583,672 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  | (277,224,718)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | (99,640,501)us-gaap_StockholdersEquity
Balance, end of period at Dec. 31, 2012 |  | 80,823,768 us-gaap_TemporaryEquityCarryingAmountAttributableToParent / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember |  |  |  |  |  |  |
Balance (in shares) at Dec. 31, 2012 |  |  |  |  | 545,345 us-gaap_SharesIssued / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Balance, end of period (in shares) at Dec. 31, 2012 |  | 15,038,259 us-gaap_TemporaryEquitySharesIssued / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember |  |  |  |  |  |  |
Increase (decrease) in temporary equity |  |  |  |  |  |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock |  | (80,823,768)ptct_TemporaryEquityConvertedIssuedDuringPeriodValueExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember | 60,785,363 ptct_TemporaryEquityConvertedIssuedDuringPeriodValueExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesFourSeniorPreferredStockMember | 101,681,783 ptct_TemporaryEquityConvertedIssuedDuringPeriodValueExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesFiveJuniorPreferredStockMember |  |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock (in shares) |  | (15,038,259)ptct_TemporaryEquityConvertedIssuedDuringPeriodSharesExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesOneToThreeConvertiblePreferredStockMember | 5,374,954 ptct_TemporaryEquityConvertedIssuedDuringPeriodSharesExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesFourSeniorPreferredStockMember | 8,796,002 ptct_TemporaryEquityConvertedIssuedDuringPeriodSharesExchangeOfConvertibleSecurities / us-gaap_StatementClassOfStockAxis = ptct_SeriesFiveJuniorPreferredStockMember |  |  |  |  |
Conversion of series of convertible preferred stock to common stock |  |  | (60,785,363)us-gaap_TemporaryEquityEliminationAsPartofReorganization / us-gaap_StatementClassOfStockAxis = ptct_SeriesFourSeniorPreferredStockMember | (101,681,783)us-gaap_TemporaryEquityEliminationAsPartofReorganization / us-gaap_StatementClassOfStockAxis = ptct_SeriesFiveJuniorPreferredStockMember |  |  |  |  |
Conversion of series of convertible preferred stock to common stock (in shares) |  |  | (5,374,954)us-gaap_ConversionOfStockSharesConverted1 / us-gaap_StatementClassOfStockAxis = ptct_SeriesFourSeniorPreferredStockMember | (8,796,002)us-gaap_ConversionOfStockSharesConverted1 / us-gaap_StatementClassOfStockAxis = ptct_SeriesFiveJuniorPreferredStockMember |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Reverse stock split |  |  |  |  | (540,819)us-gaap_StockIssuedDuringPeriodSharesReverseStockSplits / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Issuance and exchange of series of convertible preferred stock for series of convertible preferred stock |  |  |  |  |  | (14,857,927)ptct_AdjustmentsToAdditionalPaidInCapitalDecreaseInCarryingAmountOfRedeemablePreferredStock / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | (14,857,927)ptct_AdjustmentsToAdditionalPaidInCapitalDecreaseInCarryingAmountOfRedeemablePreferredStock
Issuance of common stock from IPO and exercise of over allotment exercise, net of offering costs |  |  |  |  | 9,628 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 131,640,060 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 131,649,688 us-gaap_StockIssuedDuringPeriodValueNewIssues
Issuance of common stock from IPO and exercise of over allotment exercise, net of offering costs (in shares) |  |  |  |  | 9,627,800 us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Conversion of series of convertible preferred stock to common stock |  |  |  |  | 14,171 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 162,452,975 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 162,467,146 us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
Conversion of series of convertible preferred stock to common stock (in shares) |  |  |  |  | 14,170,956 us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Share-based compensation expense |  |  |  |  |  | 8,427,188 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 8,427,188 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
Net loss |  |  |  |  |  |  |  | (51,573,575)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | (51,574,000)us-gaap_NetIncomeLoss
Comprehensive income (loss) |  |  |  |  |  |  | 70,393 us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember |  | 70,000 us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
Balance at Dec. 31, 2013 |  |  |  |  | 24,344 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 465,245,968 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | 70,393 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember | (328,798,293)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | 136,542,000 us-gaap_StockholdersEquity
Balance (in shares) at Dec. 31, 2013 |  |  |  |  | 23,803,282 us-gaap_SharesIssued / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Exercise of stock options |  |  |  |  | 109 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 1,195,286 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 1,195,395 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
Exercise of stock options (in shares) |  |  |  |  | 108,645 us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Vesting of restricted stocks |  |  |  |  | 373 us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | (373)us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  |
Vesting of restricted stock (in shares) |  |  |  |  | 373,200 us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Issuance of common stock from IPO and exercise of over allotment exercise, net of offering costs |  |  |  |  | 8,072 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | 235,971,025 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 235,979,097 us-gaap_StockIssuedDuringPeriodValueNewIssues
Issuance of common stock from IPO and exercise of over allotment exercise, net of offering costs (in shares) |  |  |  |  | 8,613,265 us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |
Share-based compensation expense |  |  |  |  |  | 19,309,652 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember |  |  | 19,309,652 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
Net loss |  |  |  |  |  |  |  | (93,753,493)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | (93,753,000)us-gaap_NetIncomeLoss
Comprehensive income (loss) |  |  |  |  |  |  | (807,058)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember |  | (807,058)us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent
Balance at Dec. 31, 2014 |  |  |  |  | $ 32,898 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | $ 721,721,558 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | $ (736,665)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember | $ (422,551,786)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | $ 298,467,000 us-gaap_StockholdersEquity
Balance (in shares) at Dec. 31, 2014 |  |  |  |  | 32,898,392 us-gaap_SharesIssued / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |

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