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v2.4.1.9

Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Cash flows from operating activities |  |  |
Net loss | $ (93,753)us-gaap_NetIncomeLoss | $ (51,574)us-gaap_NetIncomeLoss | $ (26,235)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 2,235 us-gaap_Depreciation | 2,396 us-gaap_Depreciation | 2,704 us-gaap_Depreciation
Change in valuation of warrant liability | 130 us-gaap_FairValueAdjustmentOfWarrants | (38)us-gaap_FairValueAdjustmentOfWarrants | (1,783)us-gaap_FairValueAdjustmentOfWarrants
Non-cash interest expense |  | 6,049 us-gaap_PaidInKindInterest | 226 us-gaap_PaidInKindInterest
Loss on extinguishment of debt |  | 130 us-gaap_GainsLossesOnExtinguishmentOfDebt |
Share-based compensation expense | 19,310 us-gaap_ShareBasedCompensation | 8,427 us-gaap_ShareBasedCompensation | 2,289 us-gaap_ShareBasedCompensation
Amortization of premiums on investments | 1,607 us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments |  |
Changes in operating assets and liabilities: |  |  |
Prepaid expenses and other current assets | (2,286)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (760)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | 2,452 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Receivables, net | (3,487)us-gaap_IncreaseDecreaseInReceivables | 56 us-gaap_IncreaseDecreaseInReceivables | 230 us-gaap_IncreaseDecreaseInReceivables
Deposits and other assets | (340)us-gaap_IncreaseDecreaseInDepositOtherAssets | 48 us-gaap_IncreaseDecreaseInDepositOtherAssets | 84 us-gaap_IncreaseDecreaseInDepositOtherAssets
Accounts payable and accrued expenses | 16,914 us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities | 5,183 us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities | (6,026)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Other long-term liabilities | (80)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities | (285)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities | 103 us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Deferred revenue | 2,476 us-gaap_IncreaseDecreaseInDeferredRevenue | (16,554)us-gaap_IncreaseDecreaseInDeferredRevenue | (21,972)us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash used in operating activities | (57,274)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (46,922)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (47,928)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities |  |  |
Purchases of fixed assets | (4,664)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (846)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (189)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of marketable securities | (247,804)us-gaap_PaymentsToAcquireMarketableSecurities | (156,045)us-gaap_PaymentsToAcquireMarketableSecurities |
Sale & redemption of marketable securities | 107,300 us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities | 29,062 us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities |
Net cash used in investing activities | (145,168)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (127,829)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (189)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities |  |  |
Payments on long-term debt | (49)us-gaap_RepaymentsOfLongTermDebt | (4,996)us-gaap_RepaymentsOfLongTermDebt | (6,944)us-gaap_RepaymentsOfLongTermDebt
Net proceeds from sale of Series One preferred stock |  |  | 29,355 us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock
Net proceeds from sale of Series Four convertible preferred stock |  | 60,785 us-gaap_SaleOfStockConsiderationReceivedOnTransaction |
Net proceeds from public offerings | 235,979 us-gaap_ProceedsFromIssuanceOfCommonStock | 131,650 us-gaap_ProceedsFromIssuanceOfCommonStock |
Proceeds from exercise of options | 1,196 us-gaap_ProceedsFromStockOptionsExercised |  |
Net cash provided by financing activities | 237,126 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 187,439 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 22,411 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rate changes on cash | (350)us-gaap_EffectOfExchangeRateOnCash |  |
Net increase (decrease) in cash and cash equivalents | 34,334 us-gaap_NetCashProvidedByUsedInContinuingOperations | 12,688 us-gaap_NetCashProvidedByUsedInContinuingOperations | (25,706)us-gaap_NetCashProvidedByUsedInContinuingOperations
Cash and cash equivalents, beginning of period | 15,414 us-gaap_CashAndCashEquivalentsAtCarryingValue | 2,726 us-gaap_CashAndCashEquivalentsAtCarryingValue | 28,432 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period | 49,748 us-gaap_CashAndCashEquivalentsAtCarryingValue | 15,414 us-gaap_CashAndCashEquivalentsAtCarryingValue | 2,726 us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of cash information |  |  |
Cash paid for interest | 1 us-gaap_InterestPaid | 367 us-gaap_InterestPaid | 1,212 us-gaap_InterestPaid
Cash paid for income taxes |  | 2 us-gaap_IncomeTaxesPaidNet | 2 us-gaap_IncomeTaxesPaidNet
Supplemental disclosures of non-cash information related to investing and financing activities |  |  |
Change in unrealized gain (loss) on marketable securities | (457)ptct_ChangeInUnrealizedGainLossOnMarketableSecurities | 70 ptct_ChangeInUnrealizedGainLossOnMarketableSecurities |
Change in carry value of preferred securities resulting from recapitalization |  | $ 3,391 ptct_ChangeInCarryingValueOfPreferredSecuritiesResultingFromRecapitalization | $ 159,954 ptct_ChangeInCarryingValueOfPreferredSecuritiesResultingFromRecapitalization

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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash -URI http://asc.fasb.org/extlink&oid=6506951 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash Equivalents -URI http://asc.fasb.org/extlink&oid=6507016 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 1 -Article 5 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6676-107765 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3044-108585 + Details
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- Definition The amount of cash paid during the current period to foreign, federal, state, and local authorities as taxes on income, net of any cash received during the current period as refunds for the overpayment of taxes. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6367179&loc=d3e4297-108586 + Details
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- Definition Cash outflow for purchase of trading, available-for-sale securities and held-to-maturity securities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=6871852&loc=d3e26853-111562 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition The cash inflow from the additional capital contribution to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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- Definition The cash inflow from issuance of preferred stocks identified as being convertible into another form of financial instrument, typically the entity's common stock. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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- Definition The cash inflow associated with the aggregate amount received by the entity through sale or maturity of marketable securities (held-to-maturity or available-for-sale) during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=6871852&loc=d3e26853-111562 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock options. This item inherently excludes any excess tax benefit, which the entity may have realized and reported separately. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (j) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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- Definition The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3291-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition Cash received on stock transaction after deduction of issuance costs. + References No definition available. + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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