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Selected quarterly financial data (Details) (USD $) In Thousands, except Per Share data, unless otherwise specified | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jul. 31, 2012 | Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2013 | Sep. 30, 2013 | Jun. 30, 2013 | Mar. 31, 2013 | Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Selected quarterly financial data |  |  |  |  |  |  |  |  |  |  |  |
Net Product Sales |  | $ 636 ptct_NetProductSales | $ 81 ptct_NetProductSales |  |  |  |  |  |  | $ 717 ptct_NetProductSales |  |
Collaboration and grant revenue |  | 12,022 ptct_CollaborationAndGrantRevenue | 1,613 ptct_CollaborationAndGrantRevenue | 1,677 ptct_CollaborationAndGrantRevenue | 9,217 ptct_CollaborationAndGrantRevenue | 4,411 ptct_CollaborationAndGrantRevenue | 16,290 ptct_CollaborationAndGrantRevenue | 6,854 ptct_CollaborationAndGrantRevenue | 7,142 ptct_CollaborationAndGrantRevenue |  |  |
Operating Expenses |  | 44,888 us-gaap_OperatingExpenses | 29,295 us-gaap_OperatingExpenses | 27,046 us-gaap_OperatingExpenses | 23,429 us-gaap_OperatingExpenses | 22,503 us-gaap_OperatingExpenses | 20,565 us-gaap_OperatingExpenses | 21,307 us-gaap_OperatingExpenses | 15,718 us-gaap_OperatingExpenses | 124,658 us-gaap_OperatingExpenses | 80,094 us-gaap_OperatingExpenses | 60,754 us-gaap_OperatingExpenses
Loss from operations |  | (32,230)us-gaap_OperatingIncomeLoss | (27,601)us-gaap_OperatingIncomeLoss | (25,369)us-gaap_OperatingIncomeLoss | (14,212)us-gaap_OperatingIncomeLoss | (18,093)us-gaap_OperatingIncomeLoss | (4,276)us-gaap_OperatingIncomeLoss | (14,453)us-gaap_OperatingIncomeLoss | (8,576)us-gaap_OperatingIncomeLoss | (99,413)us-gaap_OperatingIncomeLoss | (45,398)us-gaap_OperatingIncomeLoss | (26,808)us-gaap_OperatingIncomeLoss
Net loss |  |  |  |  |  | (17,886)us-gaap_NetIncomeLoss | (4,416)us-gaap_NetIncomeLoss | (14,587)us-gaap_NetIncomeLoss | (14,685)us-gaap_NetIncomeLoss | (93,753)us-gaap_NetIncomeLoss | (51,574)us-gaap_NetIncomeLoss | (26,235)us-gaap_NetIncomeLoss
Deemed Dividend |  |  |  |  |  |  |  |  | 18,249 ptct_DeemedDividend |  | 18,249 ptct_DeemedDividend |
Gain on exchange of convertible preferred stock in connection with recapitalization | 160,000 us-gaap_PreferredStockRedemptionDiscount |  |  |  |  |  |  |  | 3,391 us-gaap_PreferredStockRedemptionDiscount |  | 3,391 us-gaap_PreferredStockRedemptionDiscount | 159,954 us-gaap_PreferredStockRedemptionDiscount
Less beneficial conversion charge |  |  |  |  |  |  |  |  |  |  |  | (378)us-gaap_PreferredStockConversionsInducements
Net income (loss) attributable to common stockholders |  | $ (27,269)us-gaap_ProfitLoss | $ (27,282)us-gaap_ProfitLoss | $ (25,104)us-gaap_ProfitLoss | $ (14,098)us-gaap_ProfitLoss | $ (17,886)us-gaap_ProfitLoss | $ (4,416)us-gaap_ProfitLoss | $ (14,587)us-gaap_ProfitLoss | $ (29,543)us-gaap_ProfitLoss | $ (93,753)us-gaap_ProfitLoss | $ (66,432)us-gaap_ProfitLoss | $ 133,341 us-gaap_ProfitLoss
Basic net income (loss) per common share |  | $ (0.84)us-gaap_EarningsPerShareBasic | $ (0.93)us-gaap_EarningsPerShareBasic | $ (0.86)us-gaap_EarningsPerShareBasic | $ (0.58)us-gaap_EarningsPerShareBasic | $ (0.75)us-gaap_EarningsPerShareBasic | $ (0.19)us-gaap_EarningsPerShareBasic | $ (5.51)us-gaap_EarningsPerShareBasic | $ (6,527.30)us-gaap_EarningsPerShareBasic | $ (2.97)us-gaap_EarningsPerShareBasic | $ (5.18)us-gaap_EarningsPerShareBasic | $ 219.76 us-gaap_EarningsPerShareBasic
Diluted net income (loss) per common share |  | $ (0.84)us-gaap_EarningsPerShareDiluted | $ (0.93)us-gaap_EarningsPerShareDiluted | $ (0.86)us-gaap_EarningsPerShareDiluted | $ (0.58)us-gaap_EarningsPerShareDiluted | $ (0.75)us-gaap_EarningsPerShareDiluted | $ (0.19)us-gaap_EarningsPerShareDiluted | $ (5.51)us-gaap_EarningsPerShareDiluted | $ (6,527.30)us-gaap_EarningsPerShareDiluted | $ (2.97)us-gaap_EarningsPerShareDiluted | $ (5.18)us-gaap_EarningsPerShareDiluted | $ 42.50 us-gaap_EarningsPerShareDiluted

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