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Selected quarterly financial data (Tables) | 12 Months Ended
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Dec. 31, 2014
Selected quarterly financial data |
Summary of quarterly data |
|  | For the quarters ending |
|  | March 31 |  | June 30 |  | September 30 |  | December 31 |
2014: |  |  |  |  |  |  |  |  |  |  |  |  |
Net product sales |  | $ | — |  | $ | — |  | $ | 81 |  | $ | 636 |
Collaboration and grant revenue |  |  | 9,217 |  |  | 1,677 |  |  | 1,613 |  |  | 12,022 |
Operating expenses |  |  | 23,429 |  |  | 27,046 |  |  | 29,295 |  |  | 44,888 |
Loss from operations |  |  | (14,212 | ) |  | (25,369 | ) |  | (27,601 | ) |  | (32,230 | )
Net loss attributable to common stockholders |  |  | (14,098 | ) |  | (25,104 | ) |  | (27,282 | ) |  | (27,269 | )
Basic net loss per common share(1) |  | $ | (0.58 | ) | $ | (0.86 | ) | $ | (0.93 | ) | $ | (0.84 | )
Diluted net loss per common share(1) |  | $ | (0.58 | ) | $ | (0.86 | ) | $ | (0.93 | ) | $ | (0.84 | )
2013: |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and grant revenue |  | $ | 7,142 |  | $ | 6,854 |  | $ | 16,290 |  | $ | 4,411 |
Operating expenses |  |  | 15,718 |  |  | 21,307 |  |  | 20,565 |  |  | 22,503 |
Loss from operations |  |  | (8,576 | ) |  | (14,453 | ) |  | (4,276 | ) |  | (18,093 | )
Net loss |  |  | (14,685 | ) |  | (14,587 | ) |  | (4,416 | ) |  | (17,886 | )
Deemed dividend |  |  | (18,249 | ) |  | — |  |  | — |  |  | — |
Gain on exchange of convertible preferred stock in connection with recapitalization |  |  | 3,391 |  |  | — |  |  | — |  |  | — |
Net income (loss) attributable to common stockholders |  |  | (29,543 | ) |  | (14,587 | ) |  | (4,416 | ) |  | (17,886 | )
Basic net income (loss) per common share(1) |  | $ | (6,527.30 | ) | $ | (5.51 | ) | $ | (0.19 | ) | $ | (0.75 | )
Diluted net income (loss) per common share(1) |  | $ | (6,527.30 | ) | $ | (5.51 | ) | $ | (0.19 | ) | $ | (0.75 | )
(1) | The amounts were computed independently for each quarter and the sum of the quarters may not total the annual amounts.

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- Definition Tabular disclosure of the quarterly financial data in the annual financial statements. The disclosure includes financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income (loss) before extraordinary items and cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=35737889&loc=d3e1280-108306 + Details
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