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Income taxes (Tables)

12 Months Ended

Dec. 31, 2014

Income taxes

Components of Income Tax Provision

		2014			2013
Current:
U.S. Federal		$	—		$	—
U.S. State and Local			(4,890	)		2
Foreign			197			—
​	​	​	​	​	​	​	​
		$	(4,693	)	$	2
​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​

Schedule of reconciliation of the U.S. statutory income tax rate to the Company's effective tax rate

					December 31,
		2014			2013			2012
Federal income tax (benefit) at statutory rate			34.00	%		34.00	%		34.00	%
State income tax benefit, net of federal benefit			(1.60	)		5.65			3.80
Permanent differences			(0.93	)		(5.90	)		—
NOL IRC Section 382 Limitations			(21.53	)		—			—
Research and development			3.78			15.88			—
Increase to valuation allowance			9.17			(49.63	)		(35.80	)
Foreign Taxes			(18.14	)		—			—
Other			0.01			—			(2.00	)
​	​	​	​	​	​	​	​	​	​	​
Effective income tax rate			4.76	%		0.00	%		0.00	%
​	​	​	​	​	​	​	​	​	​	​

Schedule of significant components of the Company's deferred tax assets and liabilities

		2014			2013
Current:
Accrued Expense		$	611		$	333
Deferred tax assets:
Amortization			69			80
Depreciation			2,268			1,922
Deferred revenue			699			350
Federal tax credits			17,807			14,082
State tax credits			1,274			1,587
Federal net operating losses			76,933			88,188
State net operating losses			9,185			10,457
Capitalized research and development costs			10,585			12,254
Other			3,852			3,212
​	​	​	​	​	​	​	​
Total gross deferred tax assets			123,283			132,465
Less valuation allowance			(123,283	)		(132,465	)
​	​	​	​	​	​	​	​
Net deferred tax assets		$	—		$	—
​	​	​	​	​	​	​	​

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 9

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 2

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 740

-SubTopic 10

-Section 50

-Paragraph 12

-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319

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