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Income taxes (Details) (USD $)
In Thousands, unless otherwise specified
 12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Current:      
U.S. State and local $ (4,890)us-gaap_CurrentStateAndLocalTaxExpenseBenefit $ 2us-gaap_CurrentStateAndLocalTaxExpenseBenefit  
Foreign 197us-gaap_CurrentForeignTaxExpenseBenefit    
Current Income Tax Expense (Benefit), Total (4,693)us-gaap_CurrentIncomeTaxExpenseBenefit 2us-gaap_CurrentIncomeTaxExpenseBenefit  
Reconciliation of the U.S. statutory income tax rate to the entity's effective tax rate      
Federal income tax (benefit) at statutory rate (as a percent) 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
State income tax benefit, net of federal benefit (as a percent) (1.60%)us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes 5.65%us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes 3.80%us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
Permanent differences (as a percent) (0.93%)ptct_EffectiveIncomeTaxRateReconciliationPermanentDifferences (5.90%)ptct_EffectiveIncomeTaxRateReconciliationPermanentDifferences  
NOL IRC Section 382 Limitations (21.53%)ptct_EffectiveIncomeTaskRateReconciliationNetOperatingLossesLimitation    
Research and development (as a percent) 3.78%us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment 15.88%us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment  
Increase to valuation allowance (as a percent) 9.17%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance (49.63%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance (35.80%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
Foreign Taxes (18.14%)us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential    
Other (as a percent) 0.01%us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments   (2.00%)us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments
Effective income tax rate (as a percent) 4.76%us-gaap_EffectiveIncomeTaxRateContinuingOperations 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations
Deferred tax assets:      
Amortization 69ptct_DeferredTaxAssetsAmortization 80ptct_DeferredTaxAssetsAmortization  
Depreciation 2,268us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment 1,922us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment  
Accrued expense 611us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities 333us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities  
Deferred revenue 699us-gaap_DeferredTaxAssetsDeferredIncome 350us-gaap_DeferredTaxAssetsDeferredIncome  
Federal tax credits 17,807ptct_DeferredTaxAssetsTaxCreditFederal 14,082ptct_DeferredTaxAssetsTaxCreditFederal  
State tax credits 1,274ptct_DeferredTaxAssetsTaxCreditState 1,587ptct_DeferredTaxAssetsTaxCreditState  
Federal net operating losses 76,933us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsDomestic 88,188us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsDomestic  
State net operating losses 9,185us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal 10,457us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal  
Capitalized research and development costs 10,585ptct_DeferredTaxAssetsDeferredExpenseCapitalizedResearchAndDevelopmentCosts 12,254ptct_DeferredTaxAssetsDeferredExpenseCapitalizedResearchAndDevelopmentCosts  
Other 3,852us-gaap_DeferredTaxAssetsOther 3,212us-gaap_DeferredTaxAssetsOther  
Total gross deferred tax assets 123,283us-gaap_DeferredTaxAssetsGross 132,465us-gaap_DeferredTaxAssetsGross  
Less valuation allowance $ 123,283us-gaap_DeferredTaxAssetsValuationAllowance $ 132,465us-gaap_DeferredTaxAssetsValuationAllowance