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v2.4.1.9

Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 3 Months Ended
--- | ---
Mar. 31, 2015 | Mar. 31, 2014
Cash flows from operating activities |  |
Net loss | $ (37,915)us-gaap_NetIncomeLoss | $ (14,098)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 634 us-gaap_Depreciation | 588 us-gaap_Depreciation
Change in valuation of warrant liability | 41 us-gaap_FairValueAdjustmentOfWarrants | 55 us-gaap_FairValueAdjustmentOfWarrants
Amortization of premiums on investments | 486 us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments | 414 us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments
Share-based compensation expense | 9,748 us-gaap_ShareBasedCompensation | 3,705 us-gaap_ShareBasedCompensation
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (2,231)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (358)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Receivables | 1,267 us-gaap_IncreaseDecreaseInReceivables | 120 us-gaap_IncreaseDecreaseInReceivables
Deposits and other assets | 138 us-gaap_IncreaseDecreaseInDepositOtherAssets | 17 us-gaap_IncreaseDecreaseInDepositOtherAssets
Accounts payable and accrued expenses | (5,589)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities | (3,472)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Other long-term liabilities | (23)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities | (23)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Deferred revenue | (2,981)us-gaap_IncreaseDecreaseInDeferredRevenue | (386)us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash used in operating activities | (36,425)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (13,438)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities |  |
Purchases of fixed assets | (883)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (186)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of marketable securities | (19,108)us-gaap_PaymentsToAcquireMarketableSecurities | (25,354)us-gaap_PaymentsToAcquireMarketableSecurities
Sale & redemption of marketable securities | 40,598 us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities | 21,273 us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities
Net cash provided/ used in investing activities | 20,607 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (4,267)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities |  |
Payments on long-term debt |  | (37)us-gaap_RepaymentsOfLongTermDebt
Proceeds from exercise of options | 3,019 us-gaap_ProceedsFromStockOptionsExercised |
Net proceeds from public offerings |  | 118,183 us-gaap_ProceedsFromIssuanceOfCommonStock
Net cash provided by financing activities | 3,019 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 118,146 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rate changes on cash | (124)us-gaap_EffectOfExchangeRateOnCash |
Net increase/(decrease) in cash and cash equivalents | (12,923)us-gaap_NetCashProvidedByUsedInContinuingOperations | 100,441 us-gaap_NetCashProvidedByUsedInContinuingOperations
Cash and cash equivalents, beginning of period | 49,748 us-gaap_CashAndCashEquivalentsAtCarryingValue | 15,414 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period | 36,825 us-gaap_CashAndCashEquivalentsAtCarryingValue | 115,855 us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of cash information |  |
Cash paid for interest |  | 1 us-gaap_InterestPaid
Supplemental disclosures of non-cash information related to investing and financing activities |  |
Change in unrealized gain (loss) on marketable securities | $ 125 ptct_ChangeInUnrealizedGainLossOnMarketableSecurities | $ 10 ptct_ChangeInUnrealizedGainLossOnMarketableSecurities

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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash -URI http://asc.fasb.org/extlink&oid=6506951 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash Equivalents -URI http://asc.fasb.org/extlink&oid=6507016 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 1 -Article 5 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6676-107765 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3044-108585 + Details
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- Definition The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition Amount of cash inflow (outflow) of financing activities, excluding discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3574-108585 + Details
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- Definition Amount of cash inflow (outflow) of investing activities, excluding discontinued operations. Investing activity cash flows include making and collecting loans and acquiring and disposing of debt or equity instruments and property, plant, and equipment and other productive assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3574-108585 + Details
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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3536-108585 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Details
Name: | us-gaap_SupplementalCashFlowInformationAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration