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Fair value of financial instruments and marketable securities (Tables)

3 Months Ended

Mar. 31, 2015

Fair value of financial instruments and marketable securities

Schedule of financial assets and liabilities that are required to be measured at fair value on a recurring basis

		March 31, 2015
		Total			Quoted prices in active markets for identical assets (level 1)			Significant other observable inputs (level 2)			Significant unobservable inputs (level 3)
Marketable securities		$	243,642		$	—		$	243,642		$	—
Warrant liability		229			—			—			229

		December 31, 2014
		Total			Quoted  prices in active markets for identical  assets (level 1)			Significant other observable inputs (level 2)			Significant unobservable inputs (level 3)
Marketable securities		$	265,493		$	—		$	265,493		$	—
Warrant Liability		188			—			—			188

Summary of marketable securities accounted for as available-for-sale securities

		March 31, 2015
		Amortized			Gross Unrealized						Fair
		Cost			Gains			Losses			Value
Commercial paper		$	19,748		$	26		$	—		$	19,774
Corporate debt securities		186,810			44			(320		)	186,534
Government obligations		37,346			21			(33		)	37,334
		$	243,904		$	91		$	(353	)	$	243,642

		December 31, 2014
		Amortized			Gross Unrealized						Fair
		Cost			Gains			Losses			Value
Corporate debt securities		$	230,379		$	80		$	(428	)	$	230,031
Government obligations		35,501			7			(46		)	35,462
		$	265,880		$	87		$	(474	)	$	265,493

Schedule of marketable securities on the balance sheet

		March 31, 2015
		Less Than 12 Months			More Than 12 Months
Commercial paper		$	19,774		$	—
Corporate debt securities		138,306			48,228
Government obligations		11,312			26,022
Total Marketable securities		$	169,392		$	74,250

		December 31, 2014
		Less Than 12 Months			More Than 12 Months
Corporate debt securities		$	157,758		$	72,273
Government obligations		6,003			29,459
Total Marketable securities		$	163,761		$	101,732

Summary of changes in the fair value of the Company's Level 3 valuation for warrant liability

		Level 3 assets
Beginning balance as of December 31, 2014		$	188
Change in fair value of warrant liability		41
Ending balance as of March 31, 2015		$	229

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Tabular disclosure of the fair value measurement of liabilities using significant unobservable inputs (Level 3), a reconciliation of the beginning and ending balances, separately presenting changes attributable to the following: (1) total gains or losses for the period (realized and unrealized), segregating those gains or losses included in earnings (or changes in net assets), and gains or losses recognized in other comprehensive income (loss) and a description of where those gains or losses included in earnings (or changes in net assets) are reported in the statement of income (or activities); (2) purchases, sales, issues, and settlements (each type disclosed separately); and (3) transfers in and transfers out of Level 3 (for example, transfers due to changes in the observability of significant inputs) by class of liability.

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Tabular disclosure of marketable securities. This may consist of investments in certain debt and equity securities, short-term investments and other assets.

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Tabular disclosure of assets and liabilities, including [financial] instruments measured at fair value that are classified in stockholders' equity, if any, that are measured at fair value on a recurring basis. The disclosures contemplated herein include the fair value measurements at the reporting date by the level within the fair value hierarchy in which the fair value measurements in their entirety fall, segregating fair value measurements using quoted prices in active markets for identical assets (Level 1), significant other observable inputs (Level 2), and significant unobservable inputs (Level 3).

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