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Consolidated Statements of Operations (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2015	Mar. 31, 2014
Revenues:
Net product revenue	$ 5,069ptct_NetProductSales
Collaboration revenue	338ptct_CollaborationRevenue	9,147ptct_CollaborationRevenue
Grant revenue	2,075us-gaap_RevenueFromGrants	70us-gaap_RevenueFromGrants
Total revenues	7,482us-gaap_SalesRevenueNet	9,217us-gaap_SalesRevenueNet
Operating expenses:
Research and development	27,938us-gaap_ResearchAndDevelopmentExpense	15,889us-gaap_ResearchAndDevelopmentExpense
Selling, general and administrative	17,615us-gaap_GeneralAndAdministrativeExpense	7,540us-gaap_GeneralAndAdministrativeExpense
Total operating expenses	45,553us-gaap_OperatingExpenses	23,429us-gaap_OperatingExpenses
Loss from operations	(38,071)us-gaap_OperatingIncomeLoss	(14,212)us-gaap_OperatingIncomeLoss
Interest income	524us-gaap_InterestIncomeExpenseNonoperatingNet	171us-gaap_InterestIncomeExpenseNonoperatingNet
Other (expense) income, net	(368)us-gaap_OtherNonoperatingIncomeExpense	(57)us-gaap_OtherNonoperatingIncomeExpense
Net loss	$ (37,915)us-gaap_NetIncomeLoss	$ (14,098)us-gaap_NetIncomeLoss
Weighted-average shares outstanding:
Basic and diluted (in shares)	33,067,752us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted	24,492,487us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted
Net loss per share - basic and diluted (in dollars per share)	$ (1.15)us-gaap_EarningsPerShareBasicAndDiluted	$ (0.58)us-gaap_EarningsPerShareBasicAndDiluted

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