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Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2015	Mar. 31, 2014
Cash flows from operating activities
Net loss	$ (37,915)us-gaap_NetIncomeLoss	$ (14,098)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	634us-gaap_Depreciation	588us-gaap_Depreciation
Change in valuation of warrant liability	41us-gaap_FairValueAdjustmentOfWarrants	55us-gaap_FairValueAdjustmentOfWarrants
Amortization of premiums on investments	486us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments	414us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments
Share-based compensation expense	9,748us-gaap_ShareBasedCompensation	3,705us-gaap_ShareBasedCompensation
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(2,231)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets	(358)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Receivables	1,267us-gaap_IncreaseDecreaseInReceivables	120us-gaap_IncreaseDecreaseInReceivables
Deposits and other assets	138us-gaap_IncreaseDecreaseInDepositOtherAssets	17us-gaap_IncreaseDecreaseInDepositOtherAssets
Accounts payable and accrued expenses	(5,589)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	(3,472)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Other long-term liabilities	(23)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities	(23)us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Deferred revenue	(2,981)us-gaap_IncreaseDecreaseInDeferredRevenue	(386)us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash used in operating activities	(36,425)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations	(13,438)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities
Purchases of fixed assets	(883)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment	(186)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of marketable securities	(19,108)us-gaap_PaymentsToAcquireMarketableSecurities	(25,354)us-gaap_PaymentsToAcquireMarketableSecurities
Sale & redemption of marketable securities	40,598us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities	21,273us-gaap_ProceedsFromSaleAndMaturityOfMarketableSecurities
Net cash provided/ used in investing activities	20,607us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations	(4,267)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities
Payments on long-term debt		(37)us-gaap_RepaymentsOfLongTermDebt
Proceeds from exercise of options	3,019us-gaap_ProceedsFromStockOptionsExercised
Net proceeds from public offerings		118,183us-gaap_ProceedsFromIssuanceOfCommonStock
Net cash provided by financing activities	3,019us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations	118,146us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rate changes on cash	(124)us-gaap_EffectOfExchangeRateOnCash
Net increase/(decrease) in cash and cash equivalents	(12,923)us-gaap_NetCashProvidedByUsedInContinuingOperations	100,441us-gaap_NetCashProvidedByUsedInContinuingOperations
Cash and cash equivalents, beginning of period	49,748us-gaap_CashAndCashEquivalentsAtCarryingValue	15,414us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period	36,825us-gaap_CashAndCashEquivalentsAtCarryingValue	115,855us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of cash information
Cash paid for interest		1us-gaap_InterestPaid
Supplemental disclosures of non-cash information related to investing and financing activities
Change in unrealized gain (loss) on marketable securities	$ 125ptct_ChangeInUnrealizedGainLossOnMarketableSecurities	$ 10ptct_ChangeInUnrealizedGainLossOnMarketableSecurities

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Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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The cash inflow associated with the amount received from holders exercising their stock options. This item inherently excludes any excess tax benefit, which the entity may have realized and reported separately.

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