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Fair value of financial instruments and marketable securities (Details 4) - Warrants - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2015
Dec. 31, 2014
Changes in the fair value of warrant liability    
Beginning balance $ 188  
Change in fair value of warrant liability (72)  
Ending balance $ 116 $ 188
Minimum    
Assumption used to estimate the fair value of warrant liability by utilizing the Black-Scholes option-pricing model    
Volatility (as a percent) 69.00% 68.00%
Risk-free interest rate (as a percent) 0.64% 0.89%
Strike price (in dollars per share) $ 128.00 $ 128.00
Expected life 1 year 11 months 16 days 2 years 6 months
Maximum    
Assumption used to estimate the fair value of warrant liability by utilizing the Black-Scholes option-pricing model    
Volatility (as a percent) 72.00% 70.00%
Risk-free interest rate (as a percent) 1.32% 1.65%
Strike price (in dollars per share) $ 2,520.00 $ 2,520.00
Expected life 4 years 2 months 23 days 4 years 8 months 12 days
Common stock    
Assumption used to estimate the fair value of warrant liability by utilizing the Black-Scholes option-pricing model    
Fair value of shares (in dollars per share) $ 48.13 $ 51.77