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Consolidated Statements of Operations - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Revenues:        
Net product revenue $ 6,161   $ 11,230  
Collaboration revenue 207 $ 1,418 545 $ 10,565
Grant revenue 406 259 2,481 329
Total revenues 6,774 1,677 14,256 10,894
Operating expenses:        
Research and development 28,190 18,313 56,128 34,202
Selling, general and administrative 17,210 8,733 34,825 16,273
Total operating expenses 45,400 27,046 90,953 50,475
Loss from operations (38,626) (25,369) (76,697) (39,581)
Interest income 498 248 1,022 419
Other (expense)/income, net (88) 17 (456) (40)
Loss before income tax expense (38,216) (25,104) (76,131) (39,202)
Income tax expense (145)   (145)  
Net loss $ (38,361) $ (25,104) $ (76,276) $ (39,202)
Weighted-average shares outstanding:        
Basic and diluted (in shares) 33,600,653 29,332,227 33,335,674 27,976,847
Net loss per share - basic and diluted (in dollars per share) $ (1.14) $ (0.86) $ (2.29) $ (1.40)