XML 39 R24.htm IDEA: XBRL DOCUMENT
v3.3.1.900

Selected quarterly financial data (Unaudited) | 12 Months Ended
--- | ---
Dec. 31, 2015
Selected quarterly financial data (Unaudited) |
Selected quarterly financial data (Unaudited) | 17. Selected quarterly financial data (Unaudited) The following financial information reflects all normal recurring adjustments, which are, in the opinion of management, necessary for a fair statement of the results of the interim periods. Summarized quarterly data for 2015 and 2014 are as follows:
|  | For the quarters ending |
|  | March 31 |  | June 30 |  | September 30 |  | December 31 |
2015: |  |  |  |  |  |  |  |  |  |  |  |  |
Net product revenue |  | $ | 5,069 |  | $ | 6,161 |  | $ | 9,772 |  | $ | 12,694 |
Collaboration and grant revenue |  |  | 2,413 |  |  | 613 |  |  | 4 |  |  | 40 |
Operating expenses |  |  | 45,553 |  |  | 45,400 |  |  | 52,008 |  |  | 60,935 |
Loss from operations |  |  | (38,071 | ) |  | (38,626 | ) |  | (42,232 | ) |  | (48,201 | )
Net loss |  |  | (37,915 | ) |  | (38,361 | ) |  | (43,223 | ) |  | (50,948 | )
Basic and diluted net loss per common share(1) |  | $ | (1.15 | ) | $ | (1.14 | ) | $ | (1.27 | ) | $ | (1.50 | )
2014: |  |  |  |  |  |  |  |  |  |  |  |  |
Net product revenue |  | $ | — |  | $ | — |  | $ | 81 |  | $ | 636 |
Collaboration and grant revenue |  |  | 9,217 |  |  | 1,677 |  |  | 1,613 |  |  | 12,022 |
Operating expenses |  |  | 23,429 |  |  | 27,046 |  |  | 29,295 |  |  | 44,888 |
Loss from operations |  |  | (14,212 | ) |  | (25,369 | ) |  | (27,601 | ) |  | (32,230 | )
Net loss |  |  | (14,098 | ) |  | (25,104 | ) |  | (27,282 | ) |  | (27,269 | )
Basic and diluted net loss per common share(1) |  | $ | (0.58 | ) | $ | (0.86 | ) | $ | (0.93 | ) | $ | (0.84 | )
(1) | The amounts were computed independently for each quarter and the sum of the quarters may not total the annual amounts.

X
- References No definition available. + Details
Name: | us-gaap_QuarterlyFinancialInformationDisclosureAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition The entire disclosure for the quarterly financial data in the annual financial statements. The disclosure may include a tabular presentation of financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income or loss before extraordinary items and earnings per share data. It also includes an indication if the information in the note is unaudited, comments on the aggregate effect of year-end adjustments, and an explanation of matters or transactions that affect comparability or are pertinent to an understanding of the information furnished. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=6372559&loc=d3e765-108305 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=35737889&loc=d3e1280-108306 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6372559&loc=d3e725-108305 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 6 -Section G -Subsection 1 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K (SK) -Number 229 -Section 302 -Paragraph a + Details
Name: | us-gaap_QuarterlyFinancialInformationTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration