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v3.3.1.900

Summary of significant accounting policies (Details 2) $ in Thousands |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Aug. 04, 2014 state | Aug. 31, 2014 | Dec. 31, 2015 USD ($) | Dec. 31, 2014 USD ($)
Research and development costs |  |  |  |
Minimum age of Ambulatory Patient | 5 years | 5 years |  |
Number of States | state | 31 |  |  |
Deferred research and development advance payments |  |  | $ 600 | $ 900
Impairment of long-lived assets |  |  |  |
Impairment of long-lived assets |  |  | 0 |
Income Tax Expense (Benefit), Continuing Operations |  |  |  |
Income tax (expense) benefit |  |  | (485) | 4,693
Recent accounting pronouncements |  |  |  |
Unamortized debt issuance cost |  |  | $ 2,800 |
New Jersey |  |  |  |
Income Tax Expense (Benefit), Continuing Operations |  |  |  |
Income tax (expense) benefit |  |  |  | $ 4,900

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