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Stock award plan - Share Base Compensation (Details) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 6 Months Ended
Mar. 05, 2013
May 31, 2013
Jun. 30, 2016
Unvested restricted stock      
Number of options      
Granted (in shares)     141,185
Stock option      
Number of options      
Outstanding at the beginning of the period (in shares)     4,826,477
Granted (in shares)     1,403,045
Exercised (in shares)     (3,125)
Forfeited/Cancelled (in shares)     (257,015)
Outstanding at the end of the period (in shares)     5,969,382
Vested or Expected to vest at the end of the period (in shares)     3,361,980
Exercisable at the end of the period (in shares)     2,357,502
Weighted-average exercise price      
Outstanding at the beginning of the period (in dollars per share)     $ 37.20
Granted (in dollars per share)     29.06
Exercised (in dollars per share)     10.85
Forfeited/Cancelled (in dollars per share)     47.36
Outstanding at the end of the period (in dollars per share)     35.02
Vested or Expected to vest at the end of the period (in dollars per share)     35.89
Exercisable at the end of the period (in dollars per share)     $ 33.60
Weighted-average remaining contractual term      
Outstanding at the end of the period     8 years 2 months 16 days
Vested or Expected to vest at the end of the period     8 years 7 months 28 days
Exercisable at the end of the period     7 years 6 months
Aggregate intrinsic value      
Outstanding at the end of the period (in dollars)     $ 6
Vested or Expected to vest at the end of the period (in dollars)     $ 5
Valuation assumptions      
Inducement grants for non-statutory stock options     93,100
Expected dividend yield (as a percent)     0.00%
Weighted average grant date fair value (in dollars per share)     $ 17.98
Stock option | Minimum      
Valuation assumptions      
Risk-free interest rate (as a percent)     1.31%
Expected volatility (as a percent)     67.00%
Expected term     5 years 18 days
Stock option | Maximum      
Valuation assumptions      
Risk-free interest rate (as a percent)     2.24%
Expected volatility (as a percent)     71.00%
Expected term     10 years
Common stock      
Stock option plan      
Number of shares available for issuance     326,101
2009 Equity and Long Term Incentive Plan      
Stock option plan      
Number of additional shares authorized   2,500,000  
2013 Stock Incentive Plan      
Stock option plan      
Number of shares available for issuance 0    
2013 Stock Incentive Plan | Unvested restricted stock      
Stock option plan      
Number of shares of restricted stock granted 735,324    
2013 Stock Incentive Plan | Stock option      
Number of options      
Granted (in shares) 4,613    
2013 Stock Incentive Plan | Common stock      
Stock option plan      
Number of shares authorized 739,937    
2009 Equity and Long Term Incentive Plan and 2013 Stock Incentive Plan | Common stock      
Stock option plan      
Number of shares available for issuance   122,296  
2009 Equity and Long Term Incentive Plan and 2013 Stock Incentive Plan | Common stock | 1998 Employee, Director and Consultant Stock Option Plan | Maximum      
Stock option plan      
Number of shares subject to outstanding awards   3,040,444  
2013 Long Term Incentive Plan | Minimum      
Stock option plan      
Annual increase in the number of shares on the first day of the fiscal year   2,500,000  
Annual increase in the number of shares outstanding on the first day of the fiscal year (as a percent)   4.00%