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Summary of significant accounting policies (Details 2) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2014 | Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($) | Dec. 31, 2014 USD ($) state
Summary |  |  |  |
Capitalized inventory |  | $ 1,700,000 |  |
Number of states | state |  |  |  | 31
Minimum age of ambulatory patient | 5 years |  |  | 5 years
Allowance for doubtful accounts |  | 700,000 | $ 0 |
Research and development costs |  |  |  |
Deferred research and development advance payments |  | 400,000 | 600,000 |
Impairment of long-lived assets |  |  |  |
Impairment of long-lived assets |  | 0 |  |
Income Tax Expense (Benefit), Continuing Operations [Abstract] |  |  |  |
Income tax (expense) benefit |  | 569,000 | 485,000 | $ (4,693,000)
Recent accounting pronouncements |  |  |  |
Unamortized debt issuance cost |  | 2,500,000 |  |
New Jersey |  |  |  |
Income Tax Expense (Benefit), Continuing Operations [Abstract] |  |  |  |
Income tax (expense) benefit |  | $ 0 | 0 | $ 4,900,000
Long-term Debt | Accounting Standards Update 2015-03 |  |  |  |
Recent accounting pronouncements |  |  |  |
Unamortized debt issuance cost |  |  | 2,800,000 |
Deposits and Other Assets | Accounting Standards Update 2015-03 |  |  |  |
Recent accounting pronouncements |  |  |  |
Unamortized debt issuance cost |  |  | $ (2,800,000) |
Minimum |  |  |  |
Summary |  |  |  |
Gross profit margin (as percent) |  | 90.00% |  |

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