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Summary of significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2016
Accounting Policies [Abstract]  
Schedule of estimated useful life of related assets
Depreciation is computed starting when the asset is placed into service on a straight-line basis over the estimated useful life of the related asset as follows:
Leasehold improvements
Lesser of useful life or lease term
Computer equipment and software
3 years
Furniture, fixtures, and lab equipment
3 to 7 years