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Capital structure (Details 2) - Common stock - $ / shares
Dec. 31, 2016
Dec. 31, 2015
2017    
Warrants    
Warrant shares (in shares) 6,250 6,250
Exercise price (in dollars per share) $ 128.00 $ 128.00
2018    
Warrants    
Warrant shares (in shares) 7,030 7,030
Exercise price (in dollars per share) $ 128.00 $ 128.00
2019    
Warrants    
Warrant shares (in shares) 130 130
Exercise price (in dollars per share) $ 2,520.00 $ 2,520.00