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Accounts payable and accrued expenses
6 Months Ended
Jun. 30, 2017
Payables and Accruals [Abstract]  
Accounts payable and accrued expenses
Accounts payable and accrued expenses
 
Accounts payable and accrued expenses at June 30, 2017 and December 31, 2016 consist of the following:
 
 
 
June 30,
2017
 
December 31,
2016
Employee compensation, benefits, and related accruals
 
$
11,064

 
$
13,649

Consulting and contracted research
 
11,006

 
11,505

Professional fees
 
2,252

 
1,237

Sales allowance and other costs
 
23,836

 
13,245

Accounts payable
 
6,062

 
6,298

Other
 
9,776

 
2,825

 
 
$
63,996

 
$
48,759