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v3.8.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Cash flows from operating activities |  |  |
Net loss | $ (79,000) | $ (142,110) | $ (170,447)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and amortization | 17,682 | 3,290 | 2,876
Change in valuation of warrant liability | 0 | (47) | (140)
Amortization of premiums on investments | 535 | 1,885 | 2,480
Amortization of debt issuance costs | 433 | 302 | 107
Share-based compensation expense | 30,559 | 35,009 | 33,979
Non-cash interest expense | 6,755 | 6,065 | 2,146
Disposal of asset | 5 | 0 | (37)
Benefit for deferred income taxes | 199 | (199) | 0
Unrealized foreign currency transaction (gains) losses, net | (459) | 1,202 | 0
Changes in operating assets and liabilities: |  |  |
Inventory, net | (6,454) | 0 | 0
Prepaid expenses and other current assets | (1,784) | 1,171 | (2,107)
Trade receivables, net | (12,203) | (14,842) | (6,907)
Deposits and other assets | (544) | (278) | 131
Accounts payable and accrued expenses | 24,011 | 4,259 | 16,981
Other long-term liabilities | 733 | (799) | (92)
Deferred revenue | 9,469 | 1,526 | (3,307)
Net cash used in operating activities | (10,063) | (103,566) | (124,337)
Cash flows from investing activities |  |  |
Purchases of fixed assets | (3,101) | (1,776) | (2,720)
Purchases of marketable securities | (81,368) | (85,377) | (223,762)
Sale & redemption of marketable securities | 174,749 | 191,634 | 205,671
Acquisition, including transaction costs | (77,163) | 0 | 0
Net cash provided by (used in) investing activities | 13,117 | 104,481 | (20,811)
Cash flows from financing activities |  |  |
Proceeds from exercise of options | 2,182 | 968 | 8,711
Proceeds from shares issued under employee stock purchase plan | 2,468 | 0 | 0
Proceeds from issuance of secured term loan | 40,000 | 0 | 0
Proceeds from issuance of convertible notes | 0 | 0 | 150,000
Net cash provided by financing activities | 44,218 | 968 | 154,061
Effect of exchange rate changes on cash | 6,199 | (1,584) | (639)
Net increase in cash and cash equivalents | 53,471 | 299 | 8,274
Cash and cash equivalents, beginning of period | 58,321 | 58,022 | 49,748
Cash and cash equivalents, end of period | 111,792 | 58,321 | 58,022
Supplemental disclosure of cash information |  |  |
Cash paid for interest | 6,271 | 4,513 | 0
Cash paid for income taxes | 1,101 | 943 | 111
Supplemental disclosures of non-cash information related to investing and financing activities |  |  |
Change in unrealized gain (loss) on marketable securities | 225 | 386 | (202)
MidCap Financial Trust |  |  |
Cash flows from financing activities |  |  |
Debt issuance costs | (432) | 0 | 0
Convertible debt |  |  |
Cash flows from financing activities |  |  |
Debt issuance costs | $ 0 | $ 0 | $ (4,650)

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- Definition The cash outflow to acquire asset without physical form usually arising from contractual or other legal rights, excluding goodwill. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition Cash outflow for purchase of trading, available-for-sale securities and held-to-maturity securities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=82896770&loc=d3e26853-111562 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from amounts received from issuance of long-term debt that is wholly or partially secured by collateral. Excludes proceeds from tax exempt secured debt. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow associated with the aggregate amount received by the entity through sale or maturity of marketable securities (held-to-maturity or available-for-sale) during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=82896770&loc=d3e26853-111562 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3179-108585 + Details
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- Definition Amount of cash inflow from exercise of stock options granted under share-based compensation arrangement. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2A -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=96867065&loc=SL79508275-113901 + Details
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- Definition The cash inflow associated with the amount received from the stock plan during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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