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Emflaza asset acquisition - Narrative (Details) - USD ($) $ in Thousands |  | 12 Months Ended
--- | --- | ---
Apr. 20, 2017 | Dec. 31, 2017
Finite-Lived Intangible Assets [Line Items] |  |
Issuance of common stock related to acquisition |  | $ 75,191
Intellectual Property |  |
Finite-Lived Intangible Assets [Line Items] |  |
Accumulated amortization |  | $ 15,400
Intellectual Property | Marathon Pharmaceuticals, LLC |  |
Finite-Lived Intangible Assets [Line Items] |  |
Cash consideration | $ 75,000 |
Issuance of common stock related to acquisition (in shares) |  | 6,683,598
Issuance of common stock related to acquisition | 75,190 |
Acquisition costs | $ 2,163 |
Useful life | 7 years |
Non-collaborative Arrangement Transactions [Member] | Marathon Pharmaceuticals, LLC |  |
Finite-Lived Intangible Assets [Line Items] |  |
Cash consideration | $ 75,000 |
Development and regulatory milestone payments which the entity may be obligated to pay | $ 50,000 |

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