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Summary of significant accounting policies - Narrative (Details) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2014 | Dec. 31, 2017 USD ($) segment | Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($)
Segment and geographic information |  |  |  |
Number of operating segments | segment |  | 1 |  |
Minimum age of ambulatory patient | 5 years |  |  |
Allowance for doubtful accounts |  | $ 800,000 | $ 700,000 |
Deferred research and development advance payments |  | 500,000 | 400,000 |
Impairment of long-lived assets |  | 0 |  |
Summary |  |  |  |
Income tax expense |  | $ (1,335,000) | (569,000) | $ (485,000)
Renewal Of Marketing Authorization, Period |  | 1 year |  |
Long-term Debt |  |  |  |
Summary |  |  |  |
Unamortized debt issuance cost |  | $ 2,100,000 |  |
Accounting Standards Update 2015-03 | Long-term Debt |  |  |  |
Summary |  |  |  |
Unamortized debt issuance cost |  |  |  | 2,500,000
Accounting Standards Update 2015-03 | Deposits and Other Assets |  |  |  |
Summary |  |  |  |
Unamortized debt issuance cost |  |  |  | (2,500,000)
Translarna |  |  |  |
Summary |  |  |  |
Sales |  | 145,200,000 | $ 81,400,000 | $ 33,700,000
Emflaza |  |  |  |
Summary |  |  |  |
Sales |  | $ 28,800,000 |  |

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