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Fixed assets (Tables)
12 Months Ended
Dec. 31, 2017
Property, Plant and Equipment [Abstract]  
Schedule of fixed assets, net
Fixed assets, net were as follows at December 31, 2017 and 2016
 
 
December 31,
 
 
2017
 
2016
Leasehold improvements
 
$
14,078

 
$
14,038

Computer equipment and software
 
5,471

 
4,622

Furniture, fixtures, and lab equipment
 
20,776

 
19,343

Assets in process
 
895

 
353

 
 
41,220

 
38,356

Less accumulated depreciation and amortization
 
(32,844
)
 
(30,927
)
 
 
$
8,376

 
$
7,429