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Summary of significant accounting policies - Narrative (Details)	1 Months Ended	12 Months Ended
	Aug. 31, 2014	Dec. 31, 2017 USD ($) segment	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)
Segment and geographic information
Number of operating segments | segment		1
Minimum age of ambulatory patient	5 years
Allowance for doubtful accounts		$ 800,000	$ 700,000
Deferred research and development advance payments		500,000	400,000
Impairment of long-lived assets		0
Summary
Income tax expense		$ (1,335,000)	(569,000)	$ (485,000)
Renewal Of Marketing Authorization, Period		1 year
Long-term Debt
Summary
Unamortized debt issuance cost		$ 2,100,000
Accounting Standards Update 2015-03 | Long-term Debt
Summary
Unamortized debt issuance cost				2,500,000
Accounting Standards Update 2015-03 | Deposits and Other Assets
Summary
Unamortized debt issuance cost				(2,500,000)
Translarna
Summary
Sales		145,200,000	$ 81,400,000	$ 33,700,000
Emflaza
Summary
Sales		$ 28,800,000

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