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Consolidated Statements of Cash Flows (unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017
Cash flows from operating activities
Net loss	$ (28,782)	$ (46,532)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	12,243	1,448
Change in valuation of warrant liability	0	3
Non-cash interest expense	3,644	3,274
Loss on disposal of asset	0	47
Amortization of premiums and accretion of discounts on investments, net	(230)	365
Amortization of debt issuance costs	256	185
Share-based compensation expense	15,831	16,914
Unrealized foreign currency transaction (gains) losses, net	(764)	1,648
Changes in operating assets and liabilities:
Inventory	(3,393)	(2,806)
Prepaid expenses and other current assets	254	(416)
Trade receivables, net	(20,429)	(6,762)
Deposits and other assets	(419)	(463)
Accounts payable and accrued expenses	2,225	12,452
Other liabilities	485	457
Deferred revenue	3,204	4,604
Net cash used in operating activities	(15,875)	(15,582)
Cash flows from investing activities
Purchases of fixed assets	(1,187)	(579)
Purchases of marketable securities	(28,656)	(19,467)
Sale and redemption of marketable securities	35,939	144,357
Acquisition, including transaction costs	0	(76,424)
Net cash provided by investing activities	6,096	47,887
Cash flows from financing activities
Proceeds from exercise of options	3,592	535
Net proceeds from public offerings	117,874	0
Proceeds from shares issued under employee stock purchase plan	1,299	557
Debt issuance costs related to secured term loan	0	(432)
Proceeds from issuance of secured term loan	0	40,000
Net cash provided by financing activities	122,765	40,660
Effect of exchange rate changes on cash	(990)	1,725
Net increase in cash and cash equivalents	111,996	74,690
Cash and cash equivalents, beginning of period	111,792	58,321
Cash and cash equivalents, end of period	223,788	133,011
Supplemental disclosure of cash information
Cash paid for interest	3,838	2,474
Cash paid for income taxes	$ 758	$ 334

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Amount of cash outflow for purchase of marketable security.

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The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets.

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The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder.

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The cash inflow from the additional capital contribution to the entity.

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The cash inflow associated with the aggregate amount received by the entity through sale or maturity of marketable securities (held-to-maturity or available-for-sale) during the period.

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Amount of cash inflow from exercise of stock options granted under share-based compensation arrangement.

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The cash inflow associated with the amount received from the stock plan during the period.

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The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method.

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