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Subsequent events (Details) - Subsequent Event - USD ($)
shares in Thousands
Aug. 01, 2018
Jul. 19, 2018
Subsequent Event [Line Items]    
Upfront licensing fee $ 18,000,000  
Upfront licensing fee, period one, payment $ 12,000,000  
Upfront licensing fee, period one 10 days  
Upfront licensing fee, period two, payment $ 6,000,000  
Upfront licensing fee, period two 30 days  
Milestone, potential achievements, regulatory approval $ 4,000,000  
Royalty milestone payment obligations, period 12 months  
Royalty milestone payment obligations $ 10,000,000  
Breach payment, royalty, period 30 days  
Breach, period 60 days  
Maximum    
Subsequent Event [Line Items]    
Milestone, potential achievements, regulatory approval $ 8,000,000  
Agilis    
Subsequent Event [Line Items]    
Cash consideration   $ 50,000,000
Fair value of PTC common stock   $ 150,000,000
Equity interests issued and issuable, threshold   20.00%
Estimate of common stock outstanding   9,340
Revenue recognition, milestone, potential achievements   $ 60,000,000.0
Milestone, potential achievements, priority review voucher amount   535,000,000.0
Milestone, potential achievements, net sales amount   150,000,000.0
Development and regulatory milestone payments which the entity may be obligated to pay   $ 40,000,000
Agilis | Minimum    
Subsequent Event [Line Items]    
Milestone, potential achievements, product sales   2.00%
Agilis | Maximum    
Subsequent Event [Line Items]    
Milestone, potential achievements, product sales   6.00%
Affiliated Entity    
Subsequent Event [Line Items]    
Term loan, related parties   $ 10,000,000
Term loan, maximum amount, related party, availability subject to conditions   $ 10,000,000
Debt, stated interest rate, related party   3.00%
Affiliated Entity | Maximum    
Subsequent Event [Line Items]    
Debt, stated interest rate, related party   8.00%