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Business Combination - Narrative (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 23, 2018
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Jul. 23, 2018
Dec. 31, 2017
Business Acquisition [Line Items]              
Development milestone payments which the entity is obligated to pay   $ 4,500   $ 4,500      
Contingent consideration payable   218,700   218,700     $ 0
Estimated fair value of deferred consideration payable   38,200   38,200     $ 0
Agilis              
Business Acquisition [Line Items]              
Cash consideration $ 49,221            
Equity Interest Issued, number of shares (in shares) 3,500,907            
Numerator for calculation of number of shares of equity interests issued to acquire entity $ 150,000            
Trading day period 10 days            
Fair value of PTC common stock issued $ 155,860            
Development milestone payments which the entity is obligated to pay 40,000 40,000   40,000      
Contingent consideration payable 218,700 218,700   218,700      
Estimated fair value of deferred consideration payable 38,200            
Total preliminary consideration transferred $ 461,981            
Acquisition related costs   1,500          
Earnings (loss) of acquiree since acquisition date, actual   1,900          
Due from related parties           $ 10,000  
Net loss attributable to common stockholders   (52,458) $ (41,606) (89,976) $ (90,795)    
Maximum | Agilis              
Business Acquisition [Line Items]              
Development milestone payments which the entity is obligated to pay   60,000   60,000      
Milestone, potential achievements, priority review voucher amount       535,000      
Milestone, potential achievements, net sales amount   $ 150,000   $ 150,000      
Milestone, potential achievements, product sales   6.00%   6.00%      
Minimum | Agilis              
Business Acquisition [Line Items]              
Milestone, potential achievements, product sales   2.00%   2.00%      
Acquisition-related Costs | Agilis              
Business Acquisition [Line Items]              
Net loss attributable to common stockholders   $ 800   $ 1,500