Development And Regulatory Milestone Payment Obligations, Period

No definition available.

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- Definition

Represents the development milestones payments which the entity is obligated to pay under certain contractual agreements.

+ References

No definition available.

+ Details

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- Definition

Upfront Licensing Fee

+ References

No definition available.

+ Details

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- Definition

The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method.

+ References

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- Definition

The amount of identifiable intangible assets recognized as of the acquisition date.

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-Publisher FASB
-Name Accounting Standards Codification
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- Definition

Useful life of finite-lived intangible assets, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.

+ References

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-Publisher FASB
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- Definition

Amount of increase in assets, excluding financial assets and goodwill, lacking physical substance with an indefinite life, from an acquisition.

+ References

No definition available.

+ Details

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- Definition

Amount of cash outflow, not made soon after acquisition date of business combination, to settle contingent consideration liability exceeding amount recognized at acquisition date. Includes, but is not limited to, measurement period adjustment and less amount paid soon after acquisition date.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Intangible assets and goodwill - Narrative (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017	Apr. 20, 2017
Finite-Lived Intangible Assets [Line Items]
Useful life			7 years
Payment for contingent consideration liability, operating activities	$ 4,500		$ 8,400
Development milestone payments which the entity is obligated to pay	4,500		4,500
Amortization of acquired intangible asset	5,793	$ 9,716	16,815	$ 9,952
Total allocation of IPR&D assets			480,000
Goodwill	100,309		100,309		$ 0
Research and development	54,368	$ 30,024	118,337	$ 88,222
Akcea
Finite-Lived Intangible Assets [Line Items]
Upfront licensing fee	12,000		$ 12,000
Development and regulatory milestone payment obligations, period			30 days
Research and development	12,000
Non-collaborative Arrangement Transactions \| Akcea
Finite-Lived Intangible Assets [Line Items]
Development milestone payments which the entity is obligated to pay	$ 6,000		$ 6,000
Emflaza asset acquisition
Finite-Lived Intangible Assets [Line Items]
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles						$ 148,400