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Acquisitions - Narrative (Details) - USD ($) |  |  | 4 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Aug. 23, 2018 | Apr. 20, 2017 | Dec. 31, 2018 | Dec. 31, 2018 | Dec. 31, 2017
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Contingent consideration payable |  |  | $ 310,240,000 | $ 310,240,000 | $ 0
Issuance of common stock related to acquisition |  |  |  | $ 155,860,000 | 75,191,000
Useful life |  |  |  | 7 years |
Intellectual Property | Marathon Pharmaceuticals, LLC |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Cash consideration |  | $ 75,000,000 |  |  |
Issuance of common stock related to acquisition (in shares) |  | 6,683,598 |  | 6,683,598 |
Issuance of common stock related to acquisition |  | $ 75,200,000 |  |  |
Acquisition costs |  | $ 2,200,000 |  |  |
Useful life |  | 7 years |  |  |
Non-collaborative Arrangement Transactions | Marathon Pharmaceuticals, LLC |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Cash consideration |  | $ 75,000,000 |  |  |
Equity interest issued or issuable, number of shares (in shares) |  | 6,683,598 |  |  |
Numerator for calculation of number of shares of equity interests issued to acquire entity |  | $ 65,000,000 |  |  |
Trading day period |  | 15 days |  |  |
Development milestone payment obligations |  | $ 50,000,000 |  |  |
Agilis |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Cash consideration | $ 49,221,000 |  |  |  |
Equity interest issued or issuable, number of shares (in shares) | 3,500,907 |  |  |  |
Fair value of PTC common stock issued | $ 155,860,000 |  |  |  |
Estimated fair value of contingent consideration payable | 290,500,000 |  |  |  |
Deferred consideration payable | 38,100,000 |  |  |  |
Business combination, consideration | 533,681,000 |  |  |  |
Acquisition Related Costs |  |  |  | $ 1,700,000 |
Net loss attributable to common stockholders |  |  |  | $ (138,083,000) | $ (93,333,000)
Issuance of common stock related to acquisition (in shares) |  |  |  | 3,500,907 |
Numerator for calculation of number of shares of equity interests issued to acquire entity | $ 150,000,000 |  |  |  |
Trading day period | 10 days |  |  |  |
Earnings (loss) of acquire since acquisition date |  |  | (8,700,000) |  |
Development milestone payment obligations | $ 40,000,000 |  | 40,000,000 | $ 40,000,000 |
Agilis | Non-collaborative Arrangement Transactions |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Development milestone payment obligations | $ 40,000,000 |  | 40,000,000 | 40,000,000 |
Acquisition-related Costs | Agilis |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Net loss attributable to common stockholders |  |  |  | 1,700,000 |
Maximum | Agilis |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Priority review voucher amount |  |  |  | 535,000,000.0 |
Net sales milestones |  |  | $ 150,000,000 | $ 150,000,000 |
Percentage of annual net sales |  |  | 600.00% | 600.00% |
Development milestone payment obligations |  |  | $ 60,000,000.0 | $ 60,000,000.0 |
Minimum | Agilis |  |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |  |
Percentage of annual net sales |  |  | 200.00% | 200.00% |

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- Definition The pro forma net Income or Loss for the period as if the business combination or combinations had been completed at the beginning of a period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(3) -URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(2) -URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463 + Details
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- Definition This element represents acquisition-related costs incurred to effect a business combination which costs have been expensed during the period. Such costs include finder's fees; advisory, legal, accounting, valuation, and other professional or consulting fees; general administrative costs, including the costs of maintaining an internal acquisitions department; and may include costs of registering and issuing debt and equity securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 25 -Paragraph 23 -URI http://asc.fasb.org/extlink&oid=84229725&loc=d3e1043-128460 + Details
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- Definition This element represents the amount of earnings or loss of the acquiree since the acquisition date included in the consolidated income statement for the reporting period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463 + Details
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- Definition Useful life of finite-lived intangible assets, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References No definition available. + Details
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- Definition The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (b)(1) -URI http://asc.fasb.org/extlink&oid=35744584&loc=d3e6927-128479 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3213-108585 + Details
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