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Acquisitions - Schedule of purchase price (Details) - USD ($) $ in Thousands		12 Months Ended
	Apr. 20, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Finite-Lived Intangible Assets [Line Items]
Cash consideration		$ 8,433	$ 77,163	$ 0
Fair value of PTC common stock issued to Marathon (6,683,598 shares)		$ 155,860	$ 75,191
Intellectual Property | Marathon Pharmaceuticals, LLC
Finite-Lived Intangible Assets [Line Items]
Cash consideration	$ 75,000
Fair value of PTC common stock issued to Marathon (6,683,598 shares)	75,200
Acquisition costs	2,200
Total preliminary consideration transferred	$ 152,353

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