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Fair value of financial instruments and marketable securities - Hierarchy (Details) - USD ($) $ in Thousands | Mar. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | $ 206,018 | $ 58,088
Deferred consideration payable | 18,900 | 18,300
Contingent consideration payable | 330,900 | 310,240
Recurring basis | Total |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 206,018 | 58,088
Stock appreciation rights liability | 1,034 | 3,814
Deferred consideration payable | 38,200 | 37,700
Contingent consideration payable | 270,800 | 257,040
Contingent consideration payable- net sales milestones and royalties | 60,100 | 53,200
Recurring basis | Quoted prices in active markets for identical assets (level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 0 | 0
Stock appreciation rights liability | 0 | 0
Deferred consideration payable | 0 | 0
Contingent consideration payable | 0 | 0
Contingent consideration payable- net sales milestones and royalties | 0 | 0
Recurring basis | Significant other observable inputs (level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 206,018 | 58,088
Stock appreciation rights liability | 0 | 0
Deferred consideration payable | 38,200 | 37,700
Contingent consideration payable | 0 | 0
Contingent consideration payable- net sales milestones and royalties | 0 | 0
Recurring basis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 0 | 0
Stock appreciation rights liability | 1,034 | 3,814
Deferred consideration payable | 0 | 0
Contingent consideration payable | 270,800 | 257,040
Agilis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | $ 60,100 | $ 53,200

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