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Fair value of financial instruments and marketable securities - Fair Value Measurement Inputs and Valuation Techniques (Details) - USD ($) $ in Thousands | 6 Months Ended |
--- | --- | ---
Jun. 30, 2019 | Dec. 31, 2018
Financial assets and liabilities measured at fair value on recurring basis |  |
Additions | $ 0 |
SARs |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 1,960 | $ 3,814
Change in fair value | 1,961 |
Payments | (3,815) |
Commitments |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 277,400 | 257,040
Additions | 0 |
Change in fair value | 20,360 |
Payments |  |
Agilis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 58,800 | 53,200
Milestones and Royalties | Agilis |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 58,800 | 53,200
Milestones and Royalties | Agilis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 58,800 | $ 53,200
Additions | 0 |
Change in fair value | 5,600 |
Payments | $ 0 |

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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