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Business Combination - Narrative (Details) - USD ($)
$ in Thousands
 6 Months Ended
Aug. 23, 2018
Jun. 30, 2019
Dec. 31, 2018
Business Acquisition [Line Items]      
Contingent consideration payable   $ 336,200 $ 310,240
Estimated fair value of deferred consideration payable   18,800 $ 18,300
Agilis      
Business Acquisition [Line Items]      
Cash consideration $ 49,200    
Equity Interest Issued, number of shares (in shares) 3,500,907    
Numerator for calculation of number of shares of equity interests issued to acquire entity $ 150,000    
Trading day period 10 days    
Development milestone payments which the entity is obligated to pay $ 40,000    
Maximum | Agilis      
Business Acquisition [Line Items]      
Development milestone payments which the entity is obligated to pay   60,000  
Milestone, potential achievements, priority review voucher amount   535,000  
Milestone, potential achievements, net sales amount   $ 150,000  
Milestone, potential achievements, product sales   6.00%  
Minimum | Agilis      
Business Acquisition [Line Items]      
Milestone, potential achievements, product sales   2.00%