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Fair value of financial instruments and marketable securities - Fair Value Measurement Inputs and Valuation Techniques (Details) - USD ($) $ in Thousands | 9 Months Ended |
--- | --- | ---
Sep. 30, 2019 | Dec. 31, 2018
Level 3 roll forward |  |
Additions | $ 0 |
SARs |  |
Level 3 roll forward |  |
Contingent consideration payable- net sales milestones and royalties | 2,235 | $ 3,814
Change in fair value | 2,236 |
Payments | (3,815) |
Commitments |  |
Level 3 roll forward |  |
Contingent consideration payable- net sales milestones and royalties | 285,300 | 257,040
Additions | 0 |
Change in fair value | 28,260 |
Payments | 0 |
Agilis | Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Contingent consideration payable- net sales milestones and royalties | 59,600 | 53,200
Milestones and Royalties | Agilis |  |
Level 3 roll forward |  |
Contingent consideration payable- net sales milestones and royalties | 59,600 | 53,200
Milestones and Royalties | Agilis | Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Contingent consideration payable- net sales milestones and royalties | 59,600 | $ 53,200
Additions | 0 |
Change in fair value | 6,400 |
Payments | $ 0 |

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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Amount of issuances of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Amount of settlements of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Fair value of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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