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Selected quarterly financial data (Unaudited) | 12 Months Ended
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Dec. 31, 2019
Quarterly Financial Information Disclosure [Abstract] |
Selected quarterly financial data (Unaudited) | Selected quarterly financial data (Unaudited) The following financial information reflects all normal recurring adjustments, which are, in the opinion of management, necessary for a fair statement of the results of the interim periods. Summarized quarterly data for 2019 and 2018 are as follows:
|  | For the quarters ending (1)
|  | March 31 |  | June 30 |  | September 30 |  | December 31
2019: |  |  |  |  |  |  |  |  |  |  |  |
Net product revenue |  | $ | 53,054 |  |  | $ | 85,476 |  |  | $ | 71,369 |  |  | $ | 81,407 |
Collaboration and grant revenue |  | 529 |  |  | 46 |  |  | 47 |  |  | 15,052 |
Operating expenses |  | 122,723 |  |  | 124,280 |  |  | 131,891 |  |  | 169,243 |
Loss income from operations |  | (69,140 | ) |  | (38,758 | ) |  | (60,475 | ) |  | (72,784 | )
Net loss |  | (72,113 | ) |  | (41,789 | ) |  | (59,997 | ) |  | (77,677 | )
Basic and diluted net loss per common share(1) |  | $ | (1.29 | ) |  | $ | (0.75 | ) |  | $ | (1.06 | ) |  | $ | (1.37 | )
2018: |  |  |  |  |  |  |  |  |  |  |  |
Net product revenue |  | $ | 55,981 |  |  | $ | 68,170 |  |  | $ | 53,021 |  |  | $ | 85,833 |
Collaboration and grant revenue |  | 81 |  |  | 573 |  |  | 570 |  |  | 505 |
Operating expenses |  | 72,805 |  |  | 74,317 |  |  | 101,821 |  |  | 131,476 |
Loss from operations |  | (16,743 | ) |  | (5,574 | ) |  | (48,230 | ) |  | (45,138 | )
Net loss |  | (19,263 | ) |  | (9,520 | ) |  | (50,969 | ) |  | (48,330 | )
Basic and diluted net loss per common share(1) |  | $ | (0.46 | ) |  | $ | (0.21 | ) |  | $ | (1.06 | ) |  | $ | 0.96 |
(1) The amounts were computed independently for each quarter and the sum of the quarters may not total the annual amounts.

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- References No definition available. + Details
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- Definition The entire disclosure for quarterly financial data. Includes, but is not limited to, tabular presentation of financial information for fiscal quarters, effect of year-end adjustments, and an explanation of matters or transactions that affect comparability of the information. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -URI http://asc.fasb.org/topic&trid=2126967 + Details
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