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Income taxes - Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Income Tax Disclosure [Abstract] |  |
Deferred Income Taxes and Other Assets, Noncurrent | $ 0 | $ 736
Deferred tax assets: |  |
Accrued expense | 2,588 | 714
Amortization | 78,291 | 5,148
Depreciation | 991 | 1,601
Federal tax credits | 99,421 | 89,070
State tax credits | 6,489 | 5,473
Federal net operating losses | 91,010 | 62,159
State net operating losses | 1,360 | 165
Foreign net operating losses | 1,056 | 736
Capitalized research and development costs | 1,274 | 2,093
Share based compensation and other | 16,425 | 21,411
Other comprehensive loss | 1,512 | 0
Total gross deferred tax assets | 300,417 | 188,570
Less valuation allowance | (267,131) | (180,481)
Total deferred tax assets, net of valuation allowance | 33,286 | 8,089
Deferred tax liabilities: |  |
Convertible debt | (33,286) | (7,353)
Indefinite lived intangible | (130,862) | (122,032)
Total gross deferred tax liabilities | (164,148) | (129,385)
Net deferred tax assets (liabilities) | $ (130,862) | $ (121,296)

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