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Acquisitions - Schedule of purchase price (Details) - USD ($)
$ in Thousands
12 Months Ended
Apr. 20, 2017
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Finite-Lived Intangible Assets [Line Items]        
Cash consideration   $ 31,682 $ 8,433 $ 77,163
Fair value of PTC common stock issued to Marathon (6,683,598 shares)     $ 155,860 $ 75,191
Intellectual Property | Marathon Pharmaceuticals, LLC        
Finite-Lived Intangible Assets [Line Items]        
Cash consideration $ 75,000      
Fair value of PTC common stock issued to Marathon (6,683,598 shares) 75,190      
Acquisition costs 2,163      
Total consideration transferred $ 152,353