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Fair value of financial instruments and marketable securities - Hierarchy (Details) - USD ($) $ in Thousands | Jun. 30, 2020 | Dec. 31, 2019
--- | --- | ---
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | $ 340,430 | $ 398,535
Contingent consideration payable | 225,700 | 356,300
Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable- net sales milestones and royalties | 89,600 |
Recurring basis | Total |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities |  | 398,535
Equity investment in ClearPoint | 4,594 | 6,194
Stock appreciation rights liability |  | 3,186
Deferred consideration payable | 2,384 | 40,000
Contingent consideration payable | 136,100 | 290,500
Contingent consideration payable- net sales milestones and royalties | 89,600 | 65,800
Recurring basis | Quoted prices in active markets for identical assets (level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities |  | 0
Equity investment in ClearPoint | 4,594 | 6,194
Stock appreciation rights liability |  | 0
Deferred consideration payable | 0 | 0
Contingent consideration payable | 0 | 0
Contingent consideration payable- net sales milestones and royalties | 0 | 0
Recurring basis | Significant other observable inputs (level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities |  | 398,535
Equity investment in ClearPoint | 0 | 0
Stock appreciation rights liability |  | 0
Deferred consideration payable | 2,384 | 40,000
Contingent consideration payable | 0 | 0
Contingent consideration payable- net sales milestones and royalties | 0 | 0
Recurring basis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities |  | 0
Equity investment in ClearPoint | 0 | 0
Stock appreciation rights liability |  | 3,186
Deferred consideration payable | 0 | 0
Contingent consideration payable | 136,100 | $ 290,500
Marketable securities | Recurring basis | Total |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 340,430 |
Marketable securities | Recurring basis | Quoted prices in active markets for identical assets (level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 0 |
Marketable securities | Recurring basis | Significant other observable inputs (level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 340,430 |
Marketable securities | Recurring basis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 0 |
Deferred consideration payable | Recurring basis | Total |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 9,251 |
Deferred consideration payable | Recurring basis | Quoted prices in active markets for identical assets (level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 0 |
Deferred consideration payable | Recurring basis | Significant other observable inputs (level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | 9,251 |
Deferred consideration payable | Recurring basis | Significant unobservable inputs (level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities | $ 0 |

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