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Consolidated Statements of Operations (unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Revenues:        
Revenue $ 75,239 $ 85,522 $ 143,498 $ 139,105
Cost of Goods and Service, Excluding Amortization Of Intangible Assets 5,304 3,211 9,389 5,587
Operating expenses:        
Amortization of acquired intangible assets 8,731 6,575 16,679 12,652
Research and development 176,525 59,979 266,632 112,544
Selling, general and administrative 53,659 49,215 111,869 89,760
Change in the fair value of deferred and contingent consideration 7,680 5,300 8,580 26,460
Settlement of deferred and contingent consideration 10,613 0 10,613 0
Total operating expenses 262,512 124,280 423,762 247,003
Loss from operations (187,273) (38,758) (280,264) (107,898)
Interest expense, net (5,379) (2,074) (11,021) (4,362)
Other income (expense), net 11,309 (183) (2,523) (292)
Loss before income tax expense (181,343) (41,015) (293,808) (112,552)
Income tax expense (84) (774) (306) (1,350)
Net loss attributable to common stockholders $ (181,427) $ (41,789) $ (294,114) $ (113,902)
Weighted-average shares outstanding:        
Basic and diluted (in shares) 65,150,780 55,912,748 63,769,958 57,113,141
Net loss per share-basic and diluted (in dollars per share)        
Net loss per share—basic and diluted (in dollars per share) $ (2.78) $ (0.75) $ (4.61) $ (1.99)
Net product revenue        
Revenues:        
Revenue $ 75,239 $ 85,476 $ 143,435 $ 138,530
Collaboration and grant revenue        
Revenues:        
Revenue $ 0 $ 46 $ 63 $ 575