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Fair value of financial instruments and marketable securities - Fair Value Measurement Inputs and Valuation Techniques (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Dec. 31, 2019	Dec. 31, 2018
Level 3 roll forward
Additions	$ 0	$ 0
Significant unobservable inputs (level 3)
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties	89,600
SARs
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties	0	1,960	$ 3,186	$ 3,814
Change in fair value	0	1,961
Payments	(3,186)	(3,815)
Commitments
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties	136,100	277,400	290,500	257,040
Additions	0	0
Change in fair value	(15,220)	20,360
Payments	0	0
Agilis | Significant unobservable inputs (level 3)
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties			65,800
Liability, Net Sales Milestones and Royalties [Member] | Agilis
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties	89,600		65,800
Liability, Net Sales Milestones and Royalties [Member] | Agilis | Significant unobservable inputs (level 3)
Level 3 roll forward
Contingent consideration payable- net sales milestones and royalties	89,600	58,800	$ 65,800	$ 53,200
Additions	0	0
Change in fair value	23,800	5,600
Payments	$ 0	$ 0

X

- Definition

Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3).

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 820
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)
-URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258

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- Definition

Amount of issuances of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 820
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(2)
-URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258

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- Definition

Amount of settlements of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 820
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(2)
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- Definition

Fair value of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 820
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258

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- Definition

A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.

+ References

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