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Accounts payable and accrued expenses - Narrative (Details) - USD ($) $ in Thousands	Jun. 30, 2020	Dec. 31, 2019
Payables and Accruals [Abstract]
Employee compensation, benefits, and related accruals	$ 24,861	$ 38,889
Consulting and contracted research	13,452	12,969
Professional fees	3,295	3,562
Sales allowance and other costs	45,848	41,155
Sales rebates and royalties	56,870	42,997
Accounts payable	15,465	10,324
Other	4,585	9,380
Accounts payable and accrued expenses	$ 164,376	$ 159,276

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Represents the carrying value as of the balance sheet date of obligations incurred through that date and payable for consulting and contracted research.

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Sales Allowance And Other Related Costs

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Sales Rebates And Royalties, Current

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Sum of the carrying values as of the balance sheet date of obligations incurred through that date and due within one year (or the operating cycle, if longer), including liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received, taxes, interest, rent and utilities, accrued salaries and bonuses, payroll taxes and fringe benefits.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
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Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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