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Debt - Narrative (Details)
 1 Months Ended 3 Months Ended 6 Months Ended
May 05, 2017
USD ($)
Sep. 30, 2019
USD ($)
day
May 31, 2017
USD ($)
Aug. 31, 2015
USD ($)
$ / shares
Jun. 30, 2020
USD ($)
$ / shares
Jun. 30, 2020
USD ($)
$ / shares
Dec. 31, 2019
USD ($)
Long-term debt              
Long-term debt         $ 297,029,000 $ 297,029,000 $ 293,859,000
Current portion of long-term debt         $ 18,333,000 18,333,000 20,000,000
Debt instrument additional amount available for repurchase           $ 37,500,000  
Conversion price per share (in dollars per share) | $ / shares         $ 6.00 $ 6.00  
Convertible debt | 3.00% Convertible senior notes due 2022              
Long-term debt              
Net carrying amount         $ 126,730,000 $ 126,730,000 121,985,000
Debt principal amount       $ 150,000,000.0 $ 150,000,000 $ 150,000,000 150,000,000
Interest rate ( as a percent )       3.00%      
Net proceeds from issuance of convertible notes       $ 145,400,000      
Trading days, number | day   20          
Stock price trigger   130.00%          
Business days, period   5 days          
Consecutive trading-day period   5 days          
Maximum product of the closing sale price of shares of the Company's common stock and the applicable conversion rate for such trading day         98.00% 98.00%  
Conversion ratio       17.7487      
Conversion price per share (in dollars per share) | $ / shares       $ 56.34      
Convertible instruments principal and unpaid interest payable upon events of default   100.00%          
Minimum percentage of principal held by convertible debt instrument holders required to issue notice for declaration of principal and unpaid interest payable upon events of default   25.00%          
Term of the convertible notes   7 years   7 years      
Adjustments to additional paid in capital, equity component of convertible debt       $ 57,500,000      
Net deferred tax liability in connection with convertible notes       $ 22,300,000      
Fair value of convertible notes         $ 175,200,000 $ 175,200,000 171,200,000
Remaining contractual life of the convertible notes           2 years 1 month 6 days  
Convertible debt | 3.00% Convertible senior notes due 2022 | Redemption on or after August 20, 2018              
Long-term debt              
Trading days, number | day   19          
Consecutive trading days, period | day   30          
Stock price trigger   130.00%          
Redemption price   100.00%          
Sinking fund         0 $ 0  
Convertible debt | 1.50% Convertible senior notes due 2026              
Long-term debt              
Net carrying amount         170,304,000 170,304,000 163,583,000
Debt principal amount         $ 287,500,000 $ 287,500,000 $ 287,500,000
Interest rate ( as a percent )         1.50% 1.50% 1.50%
Net proceeds from issuance of convertible notes           $ 279,300,000  
Conversion ratio   19.0404          
Conversion price per share (in dollars per share) | $ / shares         $ 52.52 $ 52.52  
Term of the convertible notes         6 years 2 months 12 days    
Adjustments to additional paid in capital, equity component of convertible debt   $ 123,000,000.0          
Net deferred tax liability in connection with convertible notes         $ 25,300,000 $ 25,300,000  
Fair value of convertible notes         343,800,000 343,800,000 $ 335,000,000.0
MidCap Financial Trust              
Long-term debt              
Line of credit facility, maximum borrowing capacity     $ 60,000,000.0        
Proceeds from lines of credit $ 40,000,000.0            
Line of credit facility, additional capacity available, net product revenue threshold     20,000,000.0        
Debt issuance costs     $ 400,000        
Repayments of debt           21,700,000  
Current portion of long-term debt         $ 18,300,000 $ 18,300,000  
Debt instrument, floor interest rate     1.00%        
Debt instrument, basis spread on variable rate     6.15%        
Debt instrument, interest payment period     24 months