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Revenue recognition - Narrative (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | --- | ---
Aug. 31, 2020 USD ($) | Sep. 30, 2020 USD ($) Distributor | Sep. 30, 2019 USD ($) Distributor | Sep. 30, 2020 USD ($) Distributor segment | Sep. 30, 2019 USD ($) Distributor | Jul. 17, 2020 USD ($) | Nov. 30, 2011 USD ($)
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Number of operating segments | segment |  |  |  | 1 |  |  |
Percentage of net product sales |  | 10.00% | 10.00% | 10.00% | 10.00% |  |
Number of distributors | Distributor |  | 2 | 2 | 2 | 2 |  |
Revenue recognition, milestone, potential achievements |  |  |  |  |  | $ 362,500 |
Revenue |  | $ 118,404 | $ 71,416 | $ 261,902 | $ 210,521 |  |
Performance obligations satisfied in period |  | 2,000 | 2,300 | 6,000 | 2,300 |  |
Licensing And Collaboration Agreement |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Revenue |  | 35,000 | 100 | 35,100 | 100 |  |
Licensing And Collaboration Agreement | Research And Development Event Milestones |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Revenue recognition, milestone, potential achievements |  | 37,500 |  | 37,500 |  |  | $ 135,000
Milestone payments received | $ 15,000 |  |  |  |  |  |
Licensing And Collaboration Agreement | Sales Milestones |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Revenue recognition, milestone, potential achievements |  | 325,000 |  | 325,000 |  |  | $ 325,000
Milestone payments received | $ 20,000 |  |  |  |  |  |
Royalty revenue |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Revenue |  | 696 | 0 | 696 | 0 |  |
United States |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Net product revenue |  | 38,500 | 22,900 | 102,100 | 68,300 |  |
Non-US |  |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |  |
Net product revenue |  | $ 44,200 | $ 48,500 | $ 124,000 | $ 141,600 |  |

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