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Fair value of financial instruments and marketable securities - Fair Value Measurement Inputs and Valuation Techniques (Details) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2020 | Sep. 30, 2019
Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Additions |  | $ 0
SARs |  |
Level 3 roll forward |  |
Ending Balance | $ 0 |
SARs | Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Beginning Balance | 3,186 | 3,814
Additions | 0 |
Change in fair value | 0 | 2,236
Payments | (3,186) | (3,815)
Ending Balance | 0 | 2,235
Commitments | Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Beginning Balance | 290,500 | 257,040
Additions | 0 | 0
Change in fair value | (13,120) | 28,260
Payments | 0 | 0
Ending Balance | 138,200 | 285,300
Liability, Net Sales Milestones and Royalties | Agilis |  |
Level 3 roll forward |  |
Beginning Balance | 65,800 |
Ending Balance | 95,900 |
Liability, Net Sales Milestones and Royalties | Agilis | Significant unobservable inputs (level 3) |  |
Level 3 roll forward |  |
Beginning Balance | 65,800 | 53,200
Additions | 0 | 0
Change in fair value | 30,100 | 6,400
Payments | 0 | 0
Ending Balance | $ 95,900 | $ 59,600

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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Amount of issuances of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Amount of settlements of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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- Definition Fair value of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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