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v3.20.2

Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Common stock | Additional paid-in capital | Accumulated other comprehensive income (loss) | Accumulated deficit | Total
--- | --- | --- | --- | --- | ---
Balance (in shares) at Dec. 31, 2018 | 50,606,147 |  |  |  |
Balance at the beginning of the period at Dec. 31, 2018 | $ 51 | $ 1,288,137 | $ 1,462 | $ (938,923) | $ 350,727
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Issuance of common stock related to equity offering (in shares) | 10,102,899 |  |  |  |
Issuance of common stock related to equity offering | $ 10 | 323,746 |  |  | 323,756
Equity component of the convertible notes issuance, net |  | 119,489 |  |  | 119,489
Issuance of common stock related to rights exchange |  |  |  |  | 0
Exercised (in shares) | 645,435 |  |  |  |
Exercise of options |  | 12,195 |  |  | 12,195
Restricted stock vesting and issuance, net (in shares) | 169,792 |  |  |  |
Issuance of common stock in connection with an employee stock purchase plan (in shares) | 54,719 |  |  |  |
Issuance of common stock in connection with an employee stock purchase plan |  | 1,564 |  |  | 1,564
Share-based compensation expense |  | 30,668 |  |  | 30,668
Net loss |  |  |  | (173,899) | (173,899)
Comprehensive loss |  |  | (846) |  | (846)
Balance (in shares) at Sep. 30, 2019 | 61,578,992 |  |  |  |
Balance at the end of the period at Sep. 30, 2019 | $ 61 | 1,775,799 | 616 | (1,112,822) | 663,654
Balance (in shares) at Jun. 30, 2019 | 58,707,185 |  |  |  |
Balance at the beginning of the period at Jun. 30, 2019 | $ 58 | 1,539,530 | 1,922 | (1,052,825) | 488,685
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Issuance of common stock related to equity offering (in shares) | 2,539,174 |  |  |  |
Issuance of common stock related to equity offering | $ 3 | 99,208 |  |  | 99,211
Equity component of the convertible notes issuance, net |  | 119,489 |  |  | 119,489
Exercised (in shares) | 334,433 |  |  |  |
Exercise of options |  | 7,088 |  |  | 7,088
Restricted stock vesting and issuance, net (in shares) | (1,800) |  |  |  |
Share-based compensation expense |  | 10,484 |  |  | 10,484
Net loss |  |  |  | (59,997) | (59,997)
Comprehensive loss |  |  | (1,306) |  | (1,306)
Balance (in shares) at Sep. 30, 2019 | 61,578,992 |  |  |  |
Balance at the end of the period at Sep. 30, 2019 | $ 61 | 1,775,799 | 616 | (1,112,822) | 663,654
Balance (in shares) at Dec. 31, 2019 | 61,935,870 |  |  |  |
Balance at the beginning of the period at Dec. 31, 2019 | $ 62 | 1,795,351 | (10,584) | (1,190,499) | 594,330
Balance (in shares) at Jun. 30, 2020 | 67,240,679 |  |  |  |
Balance at the end of the period at Jun. 30, 2020 | $ 67 | 2,067,274 | (10,016) | (1,484,831) | 572,494
Balance (in shares) at Dec. 31, 2019 | 61,935,870 |  |  |  |
Balance at the beginning of the period at Dec. 31, 2019 | $ 62 | 1,795,351 | (10,584) | (1,190,499) | 594,330
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Issuance of common stock related to equity offering (in shares) | 542,470 |  |  |  |
Issuance of common stock related to equity offering | $ 1 | 28,091 |  |  | 28,092
Payments for asset acquisitions, shares (in shares) | 845,364 |  |  |  |
Payments for asset acquisitions, share, value | $ 1 | 42,868 |  |  | 42,869
Issuance of common stock related to rights exchange (in shares) | 2,821,176 |  |  |  |
Issuance of common stock related to rights exchange | $ 3 | 150,525 |  |  | 150,528
Exercised (in shares) | 1,426,026 |  |  |  |
Exercise of options | $ 1 | 32,986 |  |  | 32,987
Restricted stock vesting and issuance, net (in shares) | 179,963 |  |  |  |
Issuance of common stock in connection with an employee stock purchase plan (in shares) | 58,691 |  |  |  |
Issuance of common stock in connection with an employee stock purchase plan |  | 2,406 |  |  | 2,406
Share-based compensation expense |  | 48,909 |  |  | 48,909
Other |  |  |  | (218) | (218)
Net loss |  |  |  | (363,806) | (363,806)
Comprehensive loss |  |  | (25,143) |  | (25,143)
Balance (in shares) at Sep. 30, 2020 | 67,809,560 |  |  |  |
Balance at the end of the period at Sep. 30, 2020 | $ 68 | 2,101,136 | (35,727) | (1,554,523) | 510,954
Balance (in shares) at Jun. 30, 2020 | 67,240,679 |  |  |  |
Balance at the beginning of the period at Jun. 30, 2020 | $ 67 | 2,067,274 | (10,016) | (1,484,831) | 572,494
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Issuance of common stock related to equity offering (in shares) | 173,956 |  |  |  |
Issuance of common stock related to equity offering |  | 9,141 |  |  | 9,141
Exercised (in shares) | 391,738 |  |  |  |
Exercise of options | $ 1 | 7,942 |  |  | 7,943
Restricted stock vesting and issuance, net (in shares) | 3,187 |  |  |  |
Share-based compensation expense |  | 16,779 |  |  | 16,779
Net loss |  |  |  | (69,692) | (69,692)
Comprehensive loss |  |  | (25,711) |  | (25,711)
Balance (in shares) at Sep. 30, 2020 | 67,809,560 |  |  |  |
Balance at the end of the period at Sep. 30, 2020 | $ 68 | $ 2,101,136 | $ (35,727) | $ (1,554,523) | $ 510,954

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